主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

北京中医药大学学报 ›› 2014, Vol. 37 ›› Issue (5): 354-357.doi: 10.3969/j.issn.1006-2157.2014.05.015

• 临床研究 • 上一篇    下一篇

2型糖尿病证候要素与颈动脉粥样硬化的相关性研究

刘晶1, 周春宇1, 郭蓉娟1, 陈志刚1, 王红梅1, 陈宝鑫1, 赵晖1, 寿好长1, 盛雪2, 张岩3, 郑宏1, 张允岭1   

  1. 1 北京中医药大学东方医院 北京 100078;
    2 北京市丰台区王佐镇社区卫生服务中心;
    3 北京市丰台区蒲黄榆社区卫生服务中心
  • 收稿日期:2013-10-28 出版日期:2014-05-30 发布日期:2014-05-30
  • 通讯作者: 张允岭,男,博士,教授,主任医师,博士生导师,研究方向:中医脑病,E-mail:yunlingzhang2004@163.com
  • 作者简介:刘晶,女,在读博士生,助理研究员
  • 基金资助:
    2011年医改重大专项“卫生部脑卒中高危人群筛查与干预试点项目”;北京中医药大学科技创新团队项目(No.2011-CXTD-23)

Correlation between syndrome factors of type 2 diabetes and carotid atherosclerosis

LIU Jing1, ZHOU Chun-yu1, GUO Rong-juan1, CHEN Zhi-gang1, WANG Hong-mei1, CHEN Bao-xin1, ZHAO Hui1, SHOU Hao-chang1, SHENG Xue2, ZHANG Yan3, ZHENG Hong1, ZHANG Yun-ling1   

  1. 1 Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078;
    2 Wangzuo Community Health Center, Fengtai District, Beijing;
    3 Puhuangyu Community Health Center, Fengtai District, Beijing
  • Received:2013-10-28 Online:2014-05-30 Published:2014-05-30

摘要: 目的 研究2型糖尿病证候要素与颈动脉粥样硬化的相关性。方法 纳入1 452例2型糖尿病患者,收集中医四诊信息,运用因子分析,结合专家意见,提取该病的证候要素。同时行颈动脉超声检查,运用Logistic回归分析,进行2型糖尿病证候要素与颈动脉粥样硬化之间的相关性分析。结果 2型糖尿病的主要证候要素是阴虚与气虚,次要因素是阳虚、血瘀和痰湿,兼夹因素是热盛;病位以肝脾肾为主。调整传统危险因素后,2型糖尿病的证候要素中痰湿和血瘀与颈动脉粥样硬化检出率显著相关。结论 2型糖尿病证候要素中痰湿、血瘀的程度可能会加重颈动脉粥样硬化。

关键词: 2型糖尿病, 颈动脉粥样硬化, 证候要素

Abstract: Objective To study the correlation between syndrome factors of type 2 diabetes and carotid atherosclerosis. Methods There were 1 452 cases of type 2 diabetes chosen and data of TCM four examinations was collected. The syndrome factors were extracted with factor analysis combining experts’ opinions. The patients were given color Doppler examination of carotid artery. The correlation between syndrome factors of type 2 diabetes and carotid atherosclerosis was studied by using Logistic regression analysis. Results The main syndrome factors of type 2 diabetes were yin deficiency and qi deficiency, secondary factors were yang deficiency, blood stasis and phlegm dampness, and combined factor was excess heat. The disease positions were mainly liver, spleen and kidney. After regulating traditional risk factors, phlegm dampness and blood stasis were significantly correlated to positive rate of carotid atherosclerosis. Conclusion Among the syndrome factors of type 2 diabetes, phlegm dampness and blood stasis may exacerbate the degree of carotid atherosclerosis.

Key words: type 2 diabetes, carotid atherosclerosis, syndrome factors

中图分类号: 

  • R259.871