主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

北京中医药大学学报 ›› 2015, Vol. 38 ›› Issue (1): 63-67.doi: 10.3969/j.issn.1006-2157.2015.01.014

• 临床研究 • 上一篇    下一篇

脑卒中(含短暂性脑缺血发作)伴/不伴颅外动脉狭窄患者危险因素比较及中医证候要素分析

姬少珍1, 张允岭2#, 张志辰2, 赵晖2, 寿好长2, 高芳2, 王朝歆2, 王建伟1, 李涛1, 杨阳3, 贾蓓1, 郝颖1, 张志军4, 杨秀泉5, 张永顺6, 吴浩7   

  1. 1 北京中医药大学 北京 100029;
    2 北京中医药大学东方医院;
    3 北京中医医院顺义医院;
    4 北京市丰台区蒲黄榆社区卫生服务中心;
    5 北京市丰台区王佐社区卫生服务中心;
    6 北京市丰台区花乡社区卫生服务中心;
    7 北京市丰台区方庄社区卫生服务中心
  • 收稿日期:2014-09-12 出版日期:2015-01-30 发布日期:2015-01-30
  • 通讯作者: 张允岭,男,博士,主任医师,教授,博士生导师,主要研究方向:中医药防治中风和老年期痴呆临床及机理研究,E-mail: yunlingzhang2004@163.com
  • 作者简介:姬少珍,女,在读博士生
  • 基金资助:
    2011 年医改重大专项资助项目,北京中医药大学创新团队发展计划资助项目( No. 2011-CXTD-23),国家中医药管理局2010年度中医药行业科研专项资助项目(No.201007002),国家中医药管理局2014年度中医药行业科研专项资助项目(No.201007001),2011年北京市科技计划资助项目(No.Z111107056811040)

Risk factors and TCM syndrome elements:a comparison of stroke patients with / without extracranial artery stenosis

JI Shao-zhen1,ZHANG Yun-ling2#,ZHANG Zhi-chen2,ZHAO Hui2,SHOU Hao-chang2,GAO Fang2,WANG Chao-xin2,WANG Jian-wei1,LI Tao1,YANG Yang3,JIA Bei1,HAO Ying1,ZHANG Zhi-jun5,YANG Xiu-quan4,ZHANG Yong-shun6,WU Hao7   

  1. 1 Beijing University of Chinese Medicine, Beijing 100029;
    2 Dongfang Hospital Affiliated to Beijing University of Chinese Medicine;
    3 Shunyi Hospital of Beijing TCM Hospital;
    4 Puhuangyu Community Health Service Center, Fengtai District;
    5 Wangzuo Community Health Service Center, Fengtai District;
    6 Huaxiang Community Health Service Center, Fengtai District;
    7 Fangzhuang Community Health Service Center, Fengtai District
  • Received:2014-09-12 Online:2015-01-30 Published:2015-01-30

摘要: 目的 分析颅外动脉狭窄与脑卒中含短暂性脑缺血发作(TIA)危险因素的关系,为脑血管病防治提供依据。方法 选择既往有脑卒中(含TIA)病史的1 784例脑卒中高危人群,将其分为非颅外动脉狭窄组和颅外动脉狭窄组,比较2组人群脑卒中危险因素及中医症状、舌象、脉象。结果 非颅外动脉狭窄组既往TIA患者比例、锻炼少或轻体力劳动者所占比例高于颅外动脉狭窄组。颅外动脉狭窄组既往脑卒中患者比例、空腹血糖升高检出率、吸烟比例高于非颅外动脉狭窄组(P<0.05或P<0.01)。2组患者中医证候要素比较差异无统计学意义(P>0.05),单一中医症状分布方面,口唇紫暗、肢体笨拙、小便清长等发生率有显著差异(P<0.05或P< 0.01)。结论 颅外动脉狭窄与脑卒中、空腹血糖升高发生相关。脑卒中(含TIA)患者中医证候要素以火、气虚、阴虚、血瘀、痰、阳虚为主,颅外动脉狭窄与否并不影响中医证候要素类型及分布。

关键词: 颅外动脉狭窄, 脑卒中, TIA, 脑卒中高危因素, 中医证候要素

Abstract: Objective To provide the evidence for prevention and treatment of cerebrovascular diseases by studying the correlation between extracranial artery stenosis (EAS)and the risk factors of the stroke. Methods 1 784 patients who had history of stroke or transient ischemic attack (TIA) were divided into EAS group(n=259) and non-EAS group (n=1 525), and risk factors of stroke, TCM symptoms, tongue manifestation and pulse palpation were observed. Results The proportions of patients having history of TIA, taking little physical exercise and light physical labor in non-EAS group were higher than those in EAS group; the proportions of patients having history of stroke, suffered by high fasting blood-glucose concentration, and using tobacco in EAS group were higher than those in non-EAS group (P<0.05 or P<0.01). There was no significant difference in TCM syndrome elements between the two groups (P>0.05),however, incidence of single TCM symptoms, such as dark purple lips, physically clumsy and urine clear in large amounts showed significant difference in both groups. Conclusion EAS has high correlation with stroke, high fasting blood-glucose concentration. The major syndrome elements of stroke with TIA are fire, qi deficiency, yin deficiency, blood stasis, phlegm, yang deficiency. EAS has no effects on the types and distribution of TCM syndrome elements.

Key words: extracranial artery stenosis, stroke, transient ischemic attack, risk factors of the stroke, TCM syndrome elements

中图分类号: 

  • R255.2