主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

北京中医药大学学报 ›› 2015, Vol. 38 ›› Issue (5): 299-302.doi: 10.3969/j.issn.1006-2157.2015.05.002

• 理论研究 • 上一篇    下一篇

基于肠道微生态对中医体质理论的微观阐释*

黄腾杰,李英帅,骆斌#   

  1. 北京中医药大学基础医学院 北京 100029
  • 收稿日期:2014-12-10 出版日期:2015-05-15 发布日期:2015-05-15
  • 通讯作者: 骆斌,男,硕士,研究员,硕士生导师,主要研究方向:中医体质与男科疾病研究,E-mail:luob@bucm.edu.cn
  • 作者简介:黄腾杰,女,在读硕士生
  • 基金资助:
    *国家自然科学青年基金项目(No.81302874)

Microscopic interpretation of TCM constitutional theory using intestinal microecology*

HUANG Teng-jie, LI Ying-shuai, LUO Bin#   

  1. School of Pre-clinical Medicine, Beijing University of Chinese Medicine, Beijing 100029
  • Received:2014-12-10 Online:2015-05-15 Published:2015-05-15

摘要: 微生态学研究发现,人体体表及体内存在着大量的共生菌群,其中大部分寄居在人体肠道中。定植于宿主肠道内的菌群与宿主、环境3者之间构成了呈动态平衡的统一体。对肠道微生态学的研究主要是探讨健康人体的肠道菌群结构和功能,以及菌群结构紊乱对人体健康的影响,并用微生态干预手段引导宿主向健康方向发展。而中医学之体质是人体生命过程中,在先天禀赋和后天获得的基础上所形成的形态结构、生理功能和心理状态方面综合的、相对稳定的固有特质。由于肠道微生物参与人体诸多方面的生命活动,菌群的变化可以反映宿主的生理病理状态,采用肠道微生态学的研究方法研究中医体质,将对个体化诊疗产生重要意义。中医体质理论的4个基本原理和3个科学问题与肠道微生态学基本理论互相存在着很多关联性和阐释性。根据现代肠道微生态的研究成果,将中医体质理论与现代肠道微生态理念结合起来,对中医体质的4个基本原理和3个关键科学问题进行微观阐释。

关键词: 关键词:中医体质, 肠道微生态, 理论阐释

Abstract: Modern microecology states that there are a lot of commensal bacteria on the surface and inside human body, and most of them reside in the human intestines. The microbiota, which colonize in the gut of the host, the host, and the environment, together constitute a unity of dynamic equilibrium. Intestinal microecology is mainly to explore the structure and function of gut microbiota in the bodies of healthy human beings, to discover the influence of the structural disorder of gut microbiota on human health, and to use its intervention to guide the host to live healthily. Human’s constitution in TCM theory is considered as an inherent characteristic, which is formed on the basis of the prenatal and postnatal development of human beings, and affects morphology, physiology and psychology. The human gut microbiota are involved in many physiological and pathological activities, and their changes could reflect the physiological and pathological state of the host, so the research method of using intestinal microecology to study TCM constitution could be of important significance in the individual treatment. The four basic principles and three scientific questions of TCM constitutional theory are strongly interrelated with the basic theory of intestinal microecology, and they could serve as mutual interpretation. Based on the study result of modern intestinal microecology, this paper attempts to combine TCM constitutional theory with intestinal microecology, and offers microscopic interpretation of the four basic principles and the three key scientific questions of TCM constitutional theory.

Key words: TCM constitution, intestinal microecology, theoretical interpretation

中图分类号: 

  • R2-031