主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

北京中医药大学学报 ›› 2015, Vol. 38 ›› Issue (8): 561-565.doi: 10.3969/j.issn.1006-2157.2015.08.012

• 临床研究 • 上一篇    下一篇

抑郁症中医证候要素辨证量表研究*

郭蓉娟1, 于淼2, 王嘉麟1, 韩爱庆3, 卢明4, 张允岭1, 陈建新3, 邢佳1   

  1. 1 北京中医药大学东方医院 北京 100078;
    2 北京中医药大学第三附属医院;
    3 北京中医药大学信息中心;
    4 中国科学院自动化研究所
  • 收稿日期:2015-02-13 出版日期:2015-08-30 发布日期:2015-08-30
  • 作者简介:郭蓉娟,女,博士,主任医师,博士生导师
  • 基金资助:
    国家自然科学基金资助项目(No.81072717), 北京中医药大学创新团队项目(No.2011-CXTD-23)

Establishing a TCM pattern element identification scale for depression*

GUO Rong-juan1, YU Miao2, WANG Jia-lin1, HAN Ai-qing3, LU Ming4, ZHANG Yun-ling1, CHEN Jian-xin3, XING Jia1   

  1. 1 Dongfang Hospital,Beijing University of Chinese Medicine,Beijing 100078;
    2 The Third Affiliated Hospital,Beijing University of Chinese Medicine;
    3 Information Center,Beijing University of Chinese Medicine;
    4 Automatization Institute, Chinese Academy of Sciences
  • Received:2015-02-13 Online:2015-08-30 Published:2015-08-30

摘要: 目的 建立抑郁症中医证候要素辨证量表。方法 制定抑郁症中医症状条目池调查表,收集434例抑郁症患者的四诊资料,保留出现率≥10%的症状,基于复杂系统嫡聚堆方法提取证候要素。利用向前步进(条件)回归法进行条目筛选,形成条目池;运用二分类Logistic回归分析,确定各症状权重系数,再利用受试者工作特征(ROC)曲线确定各证候要素的诊断阈值。结果 经条目筛选最后保留有效条目共39条,在此基础上建立了抑郁症中医证候要素辨证量表。量表中共有气滞、火热、痰湿、气虚、血虚、阴虚、血瘀和阳虚8个证候要素,10分为诊断阈值。结论 抑郁症证候要素辨证量表的研制是对抑郁症证候标准化规范化进行的有益探索。

关键词: 抑郁症, 证候要素, 辨证量表

Abstract: Objective To establish a TCM pattern element identification scale for depression. Methods The Questionnaire of TCM Pattern Element Items for Depression was designed. TCM four diagnostic data were collected from 434 cases of depression, and TCM pattern elements of≥10% occurrence frequency were retained. TCM pattern elements were extracted based on Complex System Entropy Cluster. Conditional logistic regression of forward method was used for the selection of scale items. Binary logistic regression analysis was used to empower the items. Diagnostic threshold was established by receiver operating characteristic (ROC) curve. Results The TCM pattern element identification scale for depression was established based on 39 valid scale items. There are 8 pattern elements in the scale, including Qi-deficiency, blood-deficiency, Yin-deficiency, Yang-deficiency, Qi-stagnation, fire-heat, phlegm-dampness, and blood stasis. The diagnostic threshold score is 10 points. Conclusion Establishing a TCM pattern element identification scale for depression could offer a useful reference for standardization of depression patterns.

Key words: depression, TCM pattern elements, identification scale

中图分类号: 

  • R277.7