主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

北京中医药大学学报 ›› 2016, Vol. 39 ›› Issue (4): 344-349.doi: 10.3969/j.issn.1006-2157.2016.04.015

• 针灸 • 上一篇    下一篇

电针对心肌缺血损伤大鼠相关经穴皮肤温度变化影响的后效应研究*

张平1,赵国桢2,刘亚利1,嵇波1#,戴健1,路雅雯1,严明娜1, 王丹1,白红新1,孙晓敏1,许咏思1   

  1. 1 北京中医药大学针灸推拿学院 北京 100029;
    2首都医科大学
  • 收稿日期:2015-12-20 出版日期:2016-04-30 发布日期:2016-04-30
  • 通讯作者: 嵇波,女,博士,教授,博士生导师,研究方向:针灸作用规律与机理研究,E-mail:jibo678@263.net
  • 作者简介:张平,男,在读硕士生
  • 基金资助:
    *国家自然科学基金面上资助项目(No.81373558)

Post-effects of electro-acupuncture intervention on the skin temperature of the acupoints areas of the rats with myocardial ischemia*

ZHANG Ping1, ZHAO Guozhen2, LIU Yali1, JI Bo1#, DAI Jian1, LU Yawen1, YAN Mingna1, WANG Dan1, BAI Hongxin1, SUN Xiaomin1, XU Yongsi1   

  1. 1School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029;
    2 Capital Medical University
  • Received:2015-12-20 Online:2016-04-30 Published:2016-04-30

摘要: 目的 通过观察不同频率电针治疗心肌缺血大鼠后不同时间相关经脉穴位“内关”“郄门”“天泉”穴皮肤温度的变化情况,探寻针刺治疗心肌缺血损伤后其相关经脉穴位反映的后效应。方法 雄性Wistar大鼠随机分为空白对照组、假手术组、心肌缺血损伤组(简称模型组)、经穴低频电针组(简称经穴A组)和经穴高频电针组(简称经穴B组)。经穴A组、经穴B组均在成功制备模型的基础上给予电针治疗。于第3天电针治疗后,检测各组大鼠心电图,记录经穴即刻、30 min、60 min红外热像图并进行数据测量和分析。结果 心肌缺血损伤时,相关经脉穴位皮肤温度均升高;电针治疗后,各穴区温度不同程度下降,近端“天泉”“郄穴”最接近正常态相同穴区温度。电针治疗结束即刻,经穴A组双侧“内关”、双侧“郄门”、左侧“天泉”体表温度较经穴B组更接近空白对照组;电针治疗结束30 min时,经穴B组双侧“内关”“郄门”更接近空白对照组;电针治疗结束60 min时,经穴B组双侧“内关”、右侧“郄门”、右侧“天泉”更接近空白对照组。结论 低频电针或高频电针治疗后,大鼠心包经经脉线上穴区温度会下降,低频电针起效快,持续时间短,高频电针起效慢,后效应持续时间长。

关键词: 心肌缺血, 红外热成像, 皮肤温度, 针灸后效应, 大鼠

Abstract: Objective To observe the skin temperature at the area of acupoints —“Neiguan” (PC 6), “Ximen” (PC 4) and “Tianquan” (PC 2) before and after electro-acupuncturing at low and high frequency, so as to explore the post-effects of acupuncturing on the rats with myocardial ischemia. Methods Myocardial ischemia model was induced by coronary artery occlusion. Wistar female rats were divided randomly into blank group, sham group, model group, low-, and high- frequency of electro-acupuncture (low-frequency, high-frequency) groups(each n=10), with acupuncturing on the rats in low and high frequency group once daily . The infrared thermograms were recorded at immediately (0 min), 30 min and 60 min after needle withdrawl. Then the data were measured and analyzed. Results The skin temperature of all three acupoint areas of rat model increased; after acupuncturing, the skin temperature of the three acupoint areas decreased, with that of PC 2 and PC 4 near to the control group. The skin temperatures of bilateral PC 6, bilateral PC 4, left PC 2 at immediately after needle withdrawl in low-frequency group were nearer to that of control group; at 30 min, skin temperatures of bilateral PC 6 and PC 4 in high-frequency group were nearer to that of control group; at 60 min, the skin temperatures of bilateral PC 6, right PC 4 and right PC 2 were nearer to that of the control group. Conclusion The skin temperatures of acupoints at the Pericardium Meridian decreased after low or high frequency acupuncture treatment; low frequency electro-acupuncture evoked rapid effects and short duration, by contrast, high frequency electro-acupuncture was found slow onset and long duration.

Key words: myocardial ischemia, infrared thermal imaging, skin temperature, post-effects of electro-acupuncture, rats

中图分类号: 

  • R285.5