主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

北京中医药大学学报 ›› 2016, Vol. 39 ›› Issue (7): 610-613.doi: 10.3969/j.issn.1006-2157.2016.07.016

• 临床研究 • 上一篇    下一篇

原发性干燥综合征合并肺间质病变中医证候与高分辨CT特征的研究*

刘洋1,董振华2#,郝伟欣2   

  1. 1 北京积水潭医院 北京 100035;
    2中国医学科学院 北京协和医学院
  • 收稿日期:2016-02-11 出版日期:2016-07-30 发布日期:2016-07-30
  • 通讯作者: 董振华,男,主任医师,硕士生导师,研究方向: 中医、中西医结合治疗风湿免疫病,E-mail:pumcdzh@163.com
  • 作者简介:刘洋,女,硕士,住院医师
  • 基金资助:
    *北京市自然科学基金资助项目(No.7132198)

Relationship between TCM patterns and high-resolution CT imaging features of primary Sjogren’s syndrome patients with interstitial lung disease*

LIU Yang1, DONG Zhenhua2#, HAO Weixin2   

  1. 1 Beijing Jishuitan Hospital,Beijing 100035;
    2 Peking Union Medical Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences
  • Received:2016-02-11 Online:2016-07-30 Published:2016-07-30

摘要: 目的 分析原发性干燥综合征合并肺间质病变(pSS-ILD)患者中医临床证候分布特点及与胸部高分辨CT(HRCT)表现之间的关系。方法 对75例pSS-ILD患者的中医证候分布、胸部HRCT分期分布情况、二者之间的关系进行回顾性分析。结果 本病可分为虚证、实证、虚实夹杂证,进而分为8种证型。主要以肺气阴两虚证(29.3%)、肺气阴两虚夹痰证(28%)2种证型最为多见,且随着胸部HRCT病变程度的加重,肺气阴两虚证愈发突显(85.7%,P=0.020)。结论 本病病机以本虚标实、虚实夹杂为主,证型分布与胸部HRCT的病变程度具有一定的相关性。

关键词: 干燥综合征, 间质性肺病, 中医证候, 胸部高分辨CT

Abstract: Objective To analyze the relationship between the clinical manifestations of TCM patterns and high-resolution CT (HRCT) imaging features in primary Sjogren’s syndrome (pSS) patients with interstitial lung disease(pSS-ILD).Methods A retrospective study on 75 cases with pSS-ILD was conducted to analyze the distribution of TCM patterns and chest HRCT staging and their correlation. Results Among 75 cases, there were three principal TCM patterns, which were deficiency pattern, excess pattern and deficiency-excess complex pattern.They could be further divided into 8 patterns in which and lung qi and yin deficiency pattern were the most frequent(29.3%), lung qi and yin deficiency with phlegm obstructing lung pattern(28%). Correlation analysis showed that the more severe the lesion degree of HRCT imaging was, the more frequent the lung qi and yin deficiency pattern was(85.7%, P=0.020).Conclusion TCM pathogenesis of pSS-ILD is a deficiency-excess complex pattern with a deficiency root and excess manifestation. There is certain relevance between TCM pattern and the lesion degree in HRCT imaging.

Key words: Sjogren’s syndrome, interstitial lung disease, TCM patterns, chest high-resolution CT

中图分类号: 

  • R241