主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

北京中医药大学学报 ›› 2018, Vol. 41 ›› Issue (11): 885-889.doi: 10.3969/j.issn.1006-2157.2018.11.001

• 专家述评 •    下一篇

从中医学视角看慢性胃炎“炎-癌转化”*

丁霞1, 魏玮2, 沈洪3, 苏泽琦1   

  1. 1 北京中医药大学 北京 100029;
    2 中国中医科学院望京医院;
    3 南京中医药大学附属医院
  • 收稿日期:2018-07-15 出版日期:2018-11-30 发布日期:2018-11-30
  • 作者简介:丁霞,女,博士,教授、主任医师,博士生导师
  • 基金资助:
    *国家自然科学基金重点项目(No.81630080),国家自然科学青年科学基金项目(No.81703931),北京中央高校基本科研业务费专项资金资助(No.2017-JYB-JS-023),国家自然科学基金重大研究计划(No. 91129714),中国博士后科学基金项目(No.150905)

On inflammation-cancer transformation of chronic gastritis from view of traditional Chinese medicine*

Ding Xia1, Wei Wei2, Shen Hong3, Sun Zeqi1   

  1. 1 Beijing University of Chinese Medicine, Beijing 100029, China;
    2 Wangjing Hospital, China Academy of Chinese Medicine Sciences, Beijing 100102, China;
    3 Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu 210029, China
  • Received:2018-07-15 Online:2018-11-30 Published:2018-11-30
  • Supported by:
    National Natural Science Foundation of China (No. 81630080), National Natural Science Foundation for Youths (No. 81703931); Fundamental Research Funds for the Central Universities in Beijing (No. 2017-JYB-JS-023), Major Research plan of the National Natural Science Foundation of China (No. 91129714), China Postdoctoral Science Foundation (No.150905)

摘要: 慢性胃炎“炎-癌转化”是慢性非可控性炎症向癌症恶性转化的经典模型,中医药在延缓、阻断、逆转该疾病进展过程中具有重要作用。本文从中医学视角,对慢性胃炎“炎-癌转化”的中医学认识和中医药在控制慢性胃炎“炎-癌转化”疾病进展中的作用、价值、瓶颈问题及对策进行了阐述。现阶段,对于慢性胃炎“炎-癌转化”的中医药论述相对较少,还未形成系统的研究成果,但中医学“动态思维”和“治未病”理论在慢性胃炎“炎-癌转化”的防治中具有重要作用。中医药在去除病因、缓解患者临床症状、改善胃黏膜病理形态中具有优势,同时在控制慢性胃炎“炎-癌转化”疾病过程中具有安全性高、药物依赖性小、患者依从性好的特点,能够起到防治并举、关口前移,控制疾病进展、降低胃癌发病率的积极作用。然而,现阶段在中医药控制慢性胃炎“炎-癌转化”的过程中仍存在临床缺少系统的辨治思路、“炎-癌转化”干预时机不明确、与西药的联合作用不清晰的问题,同时科学研究方案不能体现中医药特色、缺少系统的机制探索、研究成果难以在临床转化应用的研究瓶颈,需要我们进一步思考和解决,为真正发挥中医药控制慢性胃炎“炎-癌转化”作出努力。

关键词: 慢性胃炎, 胃癌, 炎-癌转化, 中医药, 述评

Abstract: The inflammation-cancer transformation of chronic gastritis is a classical model of malignant transformation from chronic uncontrollable inflammation cancer, and traditional Chinese medicine (TCM) plays an important role in delaying, blocking and reversing the progress of this disease. From the perspective of TCM, TCM cognition on inflammation-cancer transformation of chronic gastritis, and the function, value, bottleneck problem and countermeasure of TCM in controlling thus progress are expounded. At present stage, there are relatively few TCM literatures on discussion of inflammation-cancer transformation of chronic gastritis, and no systematic research Results achieved. The TCM theory of “dynamic thinking” and “preventive treatment of disease” plays an important role in the prevention and treatment of inflammation-cancer transformation of chronic gastritis. TCM has advantages in removing causes of disease, alleviating patients’ clinical symptoms and improving the pathological morphology of gastric mucosa. In the process of controlling inflammation-cancer transformation of chronic gastritis, TCM has the characteristics of higher safety, lower drug dependence and good compliance. It is of great significance and value to control the progress of the disease and reduce the incidence of gastric cancer. However, there are still some problems including a lack of systematic ideas of differentiation and treatment in clinical practice, unclear time for intervention of inflammation-cancer transformation of chronic gastritis, and indistinct combined effects with Western medicine at the present stage. The bottleneck problems are manifested as program in scientific research cannot reflect TCM characteristics, systematic mechanism exploration is in shortage, and research Results are difficult to be applied in clinical practice. Therefore, further consideration and measures are needed in controlling inflammation-cancer transformation of chronic gastritis by TCM

Key words: chronic gastritis, gastric cancer, inflammation-cancer transformation, Chinese medicine, review

中图分类号: 

  • R259.733