主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

北京中医药大学学报 ›› 2019, Vol. 42 ›› Issue (11): 963-968.doi: 10.3969/j.issn.1006-2157.2019.11.013

• 临床研究 • 上一篇    

不同时间点冠心病痰瘀互结证与非痰瘀互结证舌诊参数的比较研究*

王彬1, 方格1, 任琦1, 周小文1, 李先涛1#, 于春泉2   

  1. 1 广州中医药大学基础医学院 广东 510006;
    2 天津中医药大学
  • 收稿日期:2019-05-15 出版日期:2019-11-30 发布日期:2019-12-03
  • 通讯作者: 李先涛,男,研究员,博士生导师,研究方向:心脑血管疾病流行病学及防治,E-mail:Lxt150@126.com
  • 作者简介:王彬,男,在读硕士生
  • 基金资助:
    * 国家重点基础研究发展计划(973计划)资助项目(No.2014CB542901)

A comparative study on tongue diagnostic parameters between phlegm-stasis binding pattern and non-phlegm-stasis binding pattern of coronary heart disease at different time points*

Wang Bin1, Fang Ge1, Ren Qi1, Zhou Xiaowen1, Li Xiantao1#, Yu Chunquan2   

  1. 1 School of Basic Medicine, Guangzhou University of Chinese Medicine, Guangdong 510006, China;
    2 Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
  • Received:2019-05-15 Online:2019-11-30 Published:2019-12-03
  • Contact: Prof. Li Xiantao, Doctoral supervisor. School of Basic Medicine, Guangzhou University of Chinese Medicine, No. 232, Waihuan Donglu Road, Guangzhou University City, Panyu District, Guangzhou 510006. E-mail: Lxt150@126.com

摘要: 目的 在不同时间点通过舌诊仪对冠心病痰瘀互结证患者舌象进行测量,为冠心病痰瘀互结证的中医辨证诊断提供客观化依据。方法 选择符合纳入标准的研究对象,采用舌诊仪对舌苔颜色、舌苔面积、齿痕、瘀斑、裂纹、点刺相关的10个指标进行采集与分析。首先比较冠心病痰瘀互结证、非痰瘀互结证患者入院当天(第0天)与健康人舌象的指标;然后对入院治疗的冠心病痰瘀互结证与非痰瘀互结证患者在第0、5、10天舌象指标进行比较。结果 共采集149例患者,排除不符合纳入标准的8例,最终纳入141例,其中痰瘀互结证83例,非痰瘀互结证58例,另设置健康人组22例。对其中39例(痰瘀互结证组24例,非痰瘀互结证组15例)进行了3个时点的重复测量。冠心病痰瘀互结证组与健康人组比较,舌苔面积、舌苔G值、齿痕数量、齿痕面积、裂纹数量、裂纹长度、瘀斑数量、瘀斑面积、点刺数量、点刺面积差异有统计学意义;冠心病痰瘀互结证组与非痰瘀互结证组比较,齿痕数量、齿痕面积、瘀斑数量、瘀斑面积、点刺数量、点刺面积差异有统计学意义,但相同证候类型患者舌象指标在3个时点比较,除痰瘀互结证组点刺数量、点刺面积外,其余指标差异均无统计学意义。结论 舌诊参数提供了中医诊断客观化、量化的指标,可以作为诊断冠心病痰瘀互结证的参考依据。

关键词: 冠心病, 痰瘀互结证, 中医诊断, 舌诊仪, 舌象

Abstract: Objective To measure repeatedly the tongue manifestations at different time points in patients with coronary heart disease (CHD)-phlegm-stasis binding pattern (CHD-PSB pattern), and provide Objective evidence for differentiating and diagnosing CHD-PSB pattern based on traditional Chinese medicine (TCM).Methods The eligible subjects were chosen, and the information of 10 indexes, including tongue fur color, tongue fur area, teeth marks, ecchymosis, fissures and thorn-like protrusions, were collected and analyzed by using tongue diagnostic instrument. Firstly, the indexes of tongue manifestations were compared among CHD-PSB patients, non-CHD-PSB patients and healthy persons in the day of hospital admission (the 0th d), and then those indexes were compared between CHD-PSB patients and non-CHD-PSB patients on the 0th d, 5th d and 10th d after they were hospitalized and received treatment.Results There were totally 149 cases been chosen, among them 8 was not accordant with inclusion criteria and 141 were final eligible cases, who were divided into CHD-PSB pattern group (n=83), non-CHD-PSB pattern group (n=58), and health group (n=22) was established in addition. There were 39 cases (24 in CHD-PSB pattern group and 15 in non-CHD-PSB pattern group) received repeated measures at 3 time points. The differences in the area of tongue fur, G value of tongue fur, amount and area of teeth marks, amount and length of fissures, amount and area of ecchymosis, and amount and area of thorn-like protrusions had statistical significance between CHD-PSB pattern group and health group. The differences in amount and area of teeth marks, amount and area of ecchymosis and amount and area of thorn-like protrusions had statistical significance between CHD-PSB pattern group and non-CHD-PSB pattern group. The comparison in the measurement indexes of tongue manifestations of the same pattern types at 3 time points showed that, except of amount and area of thorn-like protrusions in CHD-PSB pattern group, the difference in other indexes had no statistical significance.Conclusion Tongue diagnostic instrument can realize the possibility of objectification and quantification of TCM diagnosis, and the measurement Results can be used as a reference for diagnosis.

Key words: coronary heart disease, phlegm-stasis binding pattern, diagnosis of Chinese medicine, tongue diagnostic instrument, tongue manifestations

中图分类号: 

  • R241.25