主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

北京中医药大学学报 ›› 2020, Vol. 43 ›› Issue (1): 84-88.doi: 10.3969/j.issn.1006-2157.2020.01.015

• 针灸 • 上一篇    

艾灸对氯吡格雷抵抗冠心病患者睡眠质量的影响评估*

张心悦1, 黄薰莹2, 哈略1, 惠鑫1, 王昊1, 赵百孝2#   

  1. 1 北京中医药大学针灸推拿学院 北京 100029;
    2 北京中医药大学中医学院
  • 收稿日期:2019-10-22 发布日期:2020-02-21
  • 通讯作者: 赵百孝,男,博士,教授,博士生导师,主要研究方向:灸法作用原理,E-mail:baixiao100@vip.sina.com
  • 作者简介:张心悦,女,在读硕士生
  • 基金资助:
    *国家自然科学基金面上资助项目(No.81574068,No.81874503)

Effects of moxibustion on sleep quality of coronary heart disease patients with clopidogrel resistance*

Zhang Xinyue1, Huang Xunying2, Ha Lue1, Hui Xin1, Wang Hao1, Zhao Baixiao2#   

  1. 1 School of Acupuncture and Moxibustion, Beijing University of Chinese Medicine, Beijing 100029, China;
    2 School of Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China
  • Received:2019-10-22 Published:2020-02-21
  • Contact: Prof. Zhao Baixiao, Ph.D., Doctoral supervisor, School of Chinese Medicine, Beijing University of Chinese Medicine. No.11, Beisanhuan East Road, Chaoyang District, Beijing 100029, China. E-mail: baixiao100@vip.sina.com
  • Supported by:
    Natural Science Foundation of China (No.81574068, No.81874503)

摘要: 目的 观察氯吡格雷抵抗冠心病患者在艾灸心俞、内关、膻中、中脘、足三里后的症状及睡眠质量改善状况。方法 此项试验预计纳入患者100例,将全部在北京老年医院心内科完成,预实验纳入氯吡格雷抵抗及伴失眠症状的冠心病患者30例,所有患者均在入组时自行填写匹兹堡睡眠指数(PSQI)量表,并记录其近1个月内引起身体不适的冠心病伴随症状。课题采用自身前后对照的研究方法,每次治疗均按照“由背及腹,由上至下”的操作顺序,先取双侧心俞穴,后取内关穴、膻中穴、中脘穴及双侧足三里穴,依序施灸。治疗频率为隔日艾灸1次,连续治疗1个月。治疗期间保持电话随访,并安排每位患者于第2周回院复诊1次,完成第2次的PSQI自我睡眠质量评估及冠心病伴随症状情况记录。观察治疗前后的匹兹堡睡眠质量指数改善情况,并以冠心病伴随症状的改善程度作为次要指标。结果 治疗2周、4周后,患者匹兹堡睡眠质量指数均有明显改善(P<0.05),其他冠心病伴随症状皆有明显减轻。结论 对于氯吡格雷抵抗的冠心病患者,艾灸其心俞、内关、膻中、中脘及足三里穴可以有效改善其睡眠质量,减轻冠心病的不适症状,有益患者的预后与康复。

关键词: 艾灸, 失眠, 冠心病, 氯吡格雷抵抗, 匹兹堡睡眠质量指数

Abstract: Objective To observe symptoms and changes in sleep quality before and after moxibustion on Xinshu (BL15), Neiguan (PC6), Danzhong (RN17), Zhongwan (RN12), Zusanli (ST36) in clopidogrel-resistant patients with coronary heart disease (CHD). Methods The project planned to enroll 100 patients in total. In this trial study, 30 CHD patients with clopidogrel resistance and insomnia have been enrolled. All patients filled in the Pittsburgh Sleep Quality Index (PSQI) scale by themselves and recorded accompanying symptoms of coronary heart disease that caused physical discomfort during the past one month. For each treatment session, the operation sequence of“back to belly, top to bottom” was followed. Moxibustion was perforned first on the bilateral Xinshu (BL75) points, then on the Neiguan (PC6) points and Danzhong (RN17) points, and then on Zhongwan (RN12) points, finally on bilateral Zusanli (ST36) acupoints. PSQI scores before and after the treatment were collected. Complications of coronary heart disease were also evaluated. Results PSQI scores significantly improved (P<0.05) both at 2 weeks and 4 weeks after the treatment. CHD related symptoms were also alleviated. Conclusion Moxibustion can significantly improve insomnia and relieve the symptoms of coronary heart disease. It could benefit the prognosis and recovery of CHD patients.

Key words: moxibustion, insomnia, coronary heart disease, clopidogrel resistance, Pittsburgh sleep quality index

中图分类号: 

  • R245.8