主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

北京中医药大学学报 ›› 2021, Vol. 44 ›› Issue (1): 14-18.doi: 10.3969/j.issn.1006-2157.2021.01.003

• 理论研究 • 上一篇    下一篇

从“脾失之卫”探讨急性放射损伤的中医病机*

王安, 王磊, 胡素敏#   

  1. 北京中医药大学中医学院,北京 100029
  • 收稿日期:2020-08-10 出版日期:2021-01-30 发布日期:2021-01-18
  • 通讯作者: #胡素敏,女,博士,教授,博士生导师,主要研究方向:中药基础理论与临床应用研究,辐射损伤的中医药防护研究,E-mail:husm@bucm.edu.cn
  • 作者简介:王安,女,博士
  • 基金资助:
    *国家自然科学基金项目(No.11675027,No.11475035),北京中医药大学重点公关项目(No.2020-JYB-ZDGG-008),国家社科基金特别委托项目(No.14@ZH001)

TCM understanding of acute radiation injury from “spleen losing its duty as the guard”*

Wang Lei, Hu Sumin#   

  1. School of Traditional Chinese Medicine,Beijing University of Chinese Medicine,Beijing 100029,China
  • Received:2020-08-10 Online:2021-01-30 Published:2021-01-18
  • Contact: Prof.Hu Sumin,Beijing University of Chinese Medicine.No.11,Beisanhuan Donglu Road,Beijing 100029.E-mail:husm@bucm.edu.cn.
  • Supported by:
    National Natural Science Foundation of China(No.11475035,11675027);Specially Commissioned Project of National Social Science Foundation(No.14@ZH001).

摘要: 目前,中医学界在急性放射损伤的病因病机及诊断治疗等方面,仍处于探索阶段,理论体系也尚未构建完整,这在很大程度上限制了中医药在辐射防护领域的应用与发展。课题组在前期研究中,对引起急性放射损伤的电离辐射的中医病因学特点进行分析,将其命名为电离毒。基于电离毒的性质和致病特点,以及“脾为之卫”的理论内涵,本研究提出:急性放射损伤的中医核心病机是“脾为之卫”的病理表现——“脾失之卫”。我们认为:在急性放射损伤发病之初,病机为电离毒外侵,伤脾之卫;在疾病发展、变化阶段,病机为脾失之卫,百病由生;在疾病转归、预后阶段,病机为脾卫渐复,祛邪外出。充分认识急性放射损伤的中医病机,可为进一步探讨放射损伤的防治方法,提供理论基础。

关键词: 急性放射损伤, 中医病机, 脾为之卫, 脾失之卫

Abstract: The etiology,pathogenesis,diagnosis and treatment of acute radiation injury (ARI) in traditional Chinese medicine (TCM) are still being explored.The theoretical system has not been established yet,which greatly limits the application and development of TCM in radiation protection.In the previous studies,we analyzed the Chinese medicine etiology of ARI and named it ionization toxin.Based on the pathogenic characteristics of ionizing toxin,and the theoretical connotation of “spleen acting as the guard”,we conclude that the core pathogenesis of ARI is “spleen losing its duty as the guard”.At the early stage of ARI,the pathogenesis is ionization toxin injures the spleen.When it progresses,spleen loses its duty as the guard,thus leading to various diseases.At the later stages the recovering spleen starts to expel the pathological products.Understanding the pathogenesis of acute radiation injury in TCM sets the theoretical stage for prevention and treatment.

Key words: acute radiation injury, pathogenesis of TCM, spleen acting as the guard, spleen losing its duty as the guard

中图分类号: 

  • R228