主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

北京中医药大学学报 ›› 2021, Vol. 44 ›› Issue (6): 544-549.doi: 10.3969/j.issn.1006-2157.2021.06.009

• 中医体质 • 上一篇    下一篇

177例变应性鼻炎患者的中医体质类型分布以及与焦虑抑郁状态的相关性探析*

王雅琦1, 骆斌1, 赵蔚波1, 陈勃田2, 王济1#   

  1. 1 北京中医药大学国家中医体质与治未病研究院 北京 100029;
    2 北京朝阳区金盏第二社区卫生服务中心
  • 收稿日期:2021-01-13 出版日期:2021-06-30 发布日期:2021-06-25
  • 通讯作者: #王济,女,博士,教授,博士生导师,主要研究方向:中医体质学,E-mail:doctorwang2009@126.com
  • 作者简介:王雅琦,女,在读硕士生
  • 基金资助:
    *国家自然科学基金面上项目(No.81973715),北京市自然科学基金面上项目(No.7202110),上海浦东新区卫健委临床中医高峰学科建设项目(No.PDZY-2018-0603)

Distribution of TCM constitution types of 177 patients with allergic rhinitis and its correlation with anxiety and depression*

Wang Yaqi1, Luo Bin1, Zhao Weibo1, Chen Botian2, Wang Ji1#   

  1. 1 National Institute of Traditional Chinese Medicine Constitution and Preventive Medicine, Beijing University of Chinese Medicine, Beijing 100029, China;
    2 Beijing Chaoyang District Jinzhan Second Community Health Service Centre, Beijing 100018, China
  • Received:2021-01-13 Online:2021-06-30 Published:2021-06-25
  • Contact: Prof. Wang Ji, Doctoral Supervisor. Beijing University of Chinese Medicine. No. 11 Beisanhuan Donglu Road, Chaoyang District, Beijing 100029. E-mail: doctorwang2009@126.com
  • Supported by:
    National Natural Science Foundation of China (No. 81973715), Beijing Natural Science Foundation (No. 7202110), TCM Clinical Peak Discipline Construction Project of Pudong New Area Health Commission (No. PDZY-2018-0603)

摘要: 目的 对变应性鼻炎患者中医体质类型分布及与焦虑抑郁状态的相关性进行探析。方法 选取2020年于北京中医药大学国医堂中医门诊部、北京弘医堂中医医院及同济大学附属东方医院门诊就诊的变应性鼻炎患者243例,一般人群200例,对其进行中医体质辨识及广泛性焦虑障碍量表(GAD-7)和抑郁症状群量表(PHQ-9)测评。对177例完成有效问卷的变应性鼻炎患者中医体质类型分布及与焦虑抑郁状态调查结果进行Spearman相关系数分析,对180例完成有效问卷的一般人群焦虑抑郁状态进行统计分析。结果 177例变应性鼻炎患者最常见的主要偏颇体质类型为阳虚质(22.0%),其次为特禀质(20.3%);兼夹体质频次共456次,特禀质最多(19.7%),其次为阳虚质(18.2%)。变应性鼻炎患者伴焦虑抑郁最常见的中医体质类型为阳虚质。伴轻度及以上焦虑者占28.2%,伴轻度及以上抑郁者占48.6%;伴轻度及以上焦虑和抑郁者占24.3%。180例一般人群中伴轻度及以上焦虑者占21.1%,伴轻度及以上抑郁者占30.0%,伴轻度及以上焦虑和抑郁者14.4%。所有偏颇体质均与焦虑抑郁状态正相关,排在前3位的依次是:气郁质(r=0.642,P=0.001)、痰湿质(r=0.303,P=0.001)、血瘀质(r=0.281,P<0.001)与焦虑正相关,气郁质(r=0.588,P=0.001)、气虚质(r=0.506,P=0.001)、血瘀质(r=0.447,P=0.001)与抑郁正相关,平和质与焦虑(r=-0.448,P=0.001)、抑郁(r=-0.640,P=0.001)负相关。结论 阳虚质与特禀质为变应性鼻炎最常见的中医体质类型。变应性鼻炎患者比一般人群更容易处于焦虑抑郁状态,且伴焦虑抑郁的患者最常见的中医体质类型为阳虚质。与焦虑状态相关性较高的3种中医体质类型为气郁质、痰湿质和血瘀质;与抑郁状态相关性较高的3种体质类型为气郁质、气虚质和血瘀质;平和质则与焦虑抑郁状态负相关。

关键词: 变应性鼻炎, 中医体质, 特禀质, 焦虑, 抑郁

Abstract: Objective To explore the distribution of TCM constitution types of patients with allergic rhinitis (AR) and its correlation with anxiety and depression. Methods 243 AR cases who visited Guoyitang Clinic, Beijing University of Chinese Medicine, Beijing Hongyitang TCM Hospital, and the clinic of Shanghai East Hospital, Tongji University in 2020 and 200 common subjects without AR were selected. The TCM constitution types of all the subjects were identified and they were evaluated with Generalized Anxiety Disorder(GAD-7) and Patient Health Queationaire-9(PHQ-9). The distribution of the TCM constitution types of 177 AR patients who completed the valid questionnaire and their evaluation results of anxiety and depression were analyzed with Spearman correlation coefficient, and the anxiety and depression state of 180 common subjects who completed the valid questionnaire were statistically analyzed. Results The most common TCM constitution type of the 177 AR patients was the yang-deficiency constitution (22.0%), followed by special-diathesis constitution (20.3%). The number of cases with composite TCM constitution types in the 177 AR patients was 456, of which special-diathesis constitution was the most common (19.7%), followed by yang-deficiency constitution(18.2%). The most common TCM constitution type of those with anxiety and depression among the 177 AR patients was yang-deficiency constitution. Among the 177 AR cases, those with mild to severe anxiety accounted for 28.2%, those with mild to severe depression accounted for 48.6%, and those with mild to severe anxiety and depression accounted for 24.3%. Among the 180 subjects without AR, 21.1% suffered from mild to severe anxiety, 30.0% mild to severe depression, and 14.4% mild to severe anxiety and depression. All biased TCM constitutions were related positively with anxiety and depression state. The qi-stagnation constitution (r=0.642, P=0.001), phlegm-wetness constitution (r=0.303, P=0.001), and blood-stasis constitution (r=0.281, P=0.001) were positively correlated with anxiety. The qi-stagnation constitution (r=0.588, P=0.001), qi-deficiency constitution (r=0.506, P=0.001), and blood-stasis constitution (r=0.447, P=0.001) were positively correlated with depression. The gentleness constitution was negatively correlated with anxiety (r=-0.448, P=0.001) and depression (r=-0.640, P=0.001). Conclusion The yang-deficiency constition and the special-diathesis constitution are the most common TCM constitution types of AR patients. Patients with allergic rhinitis are more likely to develop anxiety and depression than people without AR. The most common TCM constitution type of AR patients with anxiety and depression is the yang-deficiency type. Qi-stagnation constitution, phlegm-wetness constitution and blood-stasis constitution are more positively related to anxiety, and qi-stagnation constitution, qi-deficiency constitution and blood-stasis constitution are more postitive related to depression. However, gentleness constitution was negatively related to anxiety and depression.

Key words: allergic rhinitis, TCM constitution, special-diathesis constitution, anxiety, depression

中图分类号: 

  • R276.1