主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

北京中医药大学学报 ›› 2015, Vol. 38 ›› Issue (12): 838-841.doi: 10.3969/j.issn.1006-2157.2015.12.009

• 临床研究 • 上一篇    下一篇

慢病管理结合中医分期辨治提高糖尿病肾脏疾病患者生存质量的临床研究*

李同侠1, 张宁1#, 陈菲菲1, 蒋霞2, 周培一3, 卢晨4, 沙莎5   

  1. 1 中国中医科学院望京医院 北京 100102;
    2 平谷区中医院;
    3大兴区人民医院;
    4垡头卫生社区服务中心;
    5将台卫生社区服务中心
  • 收稿日期:2015-06-14 出版日期:2015-12-30 发布日期:2015-12-30
  • 通讯作者: 张宁,女,博士,主任医师,博士生导师,主要研究方向:慢性肾脏病临床及基础研究,E-mail: znice3927@126.com
  • 作者简介:李同侠,男,硕士,主治医师
  • 基金资助:
    *北京市科委首都临床特色应用研究(No.Z121107001012012),北京市中医局年度规划项目(No.JJ2011-73)

Improvement of life quality in patients with diabetic kidney disease receiving chronic illness management intervention combined with TCM treatment upon pattern identification by stage: a clinical trial*

LI Tongxia1, ZHANG Ning1#, CHEN Feifei1, JIANG Xia2, ZHOU Peiyi3, LU Chen4, SHA Sha5   

  1. 1 Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing 100102;
    2 Beijing Pinggu Hospital of TCM;
    3 People’s Hospital, Beijing Daxin District;
    4 Community Health Service Center, Jiangtai Community;
    5 Community Health Service Center, Fatou Community
  • Received:2015-06-14 Online:2015-12-30 Published:2015-12-30

摘要: 目的 观察慢病管理结合中医分期辨治对糖尿病肾脏疾病(DKD)患者生存质量的改善作用。方法 将120例DKD患者随机分为观察组和对照组,各60例,对照组给予常规西医综合治疗措施,观察组在此基础上联合慢病管理模式及中医辨证施治进行干预,疗程24个月,每6个月随访1次。采用SF-36生存量表,对2组患者生理、社会及心理3个领域的生存质量进行调查,并对结果进行统计分析。结果 24个月随访中,2组DKD患者生理功能、心理精神领域、总体生存质量均得到不同程度改善,组内各随访点与基线比较具有显著性差异(P<0.05);组间比较,从第12个月开始观察组的生理功能、总体生存质量改善优于对照组(P<0.05),至第18个月及24个月时观察组在心理精神领域和社会领域的改善也均优于对照组(P<0.05)。结论 慢病管理结合中医分期辨治通过改善DKD患者生理功能,使患者心理精神及社会关系影响在不同程度上也得到改善,进而提高了患者总体生存质量。

关键词: 慢病管理, 中医分期辨治, 糖尿病肾病, 生存质量

Abstract: Objective To evaluate the effects of chronic illness management intervention and TCM treatment based on pattern identification by stage on the quality of life in patients with diabetic kidney disease (DKD). Methods 120 DKD patients were randomly divided into the observation group and control group (n=60 in each group). Comprehensive conventional treatment was offered in both groups. Intervention of chronic illness management and TCM treatment by stage was added to the control group for a course of 24 months and one follow-up every 6 months afterwards. SF-36 Quality of Life (QoL SF-36) was used to measure changes of physiological function, psychological condition and overall life quality. Results The physiological function, psychological condition and general life quality were all improved in the two groups at different stages during the 24-month period when compared with baseline data in each group (P<0.05); Compared with the control group, the observation group started to exhibit more improvement in physiological function and general life quality at the end of 12 month (P<0.05) and maintained the superiority in psychological and social dimension between 18 and 24 months (P<0.05). Conclusion The combined intervention of chronic illness management and TCM treatment based on pattern identification at different stages may improve psychological and social functions of DKD patients on the basis of improving physiological functions, with an overall benefit of their life quality.

Key words: chronic disease management, traditional Chinese medicine pattern identification and treatment by stage, diabetic kidney disease, quality of life

中图分类号: 

  • R256.5