主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJIGN UNIVERSITY OF TRADITIONAL CHINE ›› 2014, Vol. 37 ›› Issue (3): 156-159.doi: 10.3969/j.issn.1006-2157.2014.03.003

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Study on classification of TCM syndromes of Hp-related chronic gastritis

CHEN Run-hua1, ZHANG Chang1, SU Ze-qi2, ZONG Xiang-yu3, LI Pei-cai2, DING Xia4   

  1. 1 Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078;
    2 Dongzhimen Hospital, Beijing University of Chinese Medicine;
    3 Huairou Hospital of Chinese Medicine, Beijing;
    4 Department of Medical Management, Beijing University of Chinese Medicine
  • Received:2013-12-28 Online:2014-03-30 Published:2014-03-30

Abstract: Objective To study the syndromes and syndrome factors of Helicobacter pylori (Hp)-related chronic gastritis, and discuss the expressions of TCM syndromes of Hp infection. Methods The patients with non-atrophic gastritis and atrophic gastritis (each n=200) were chosen, and their data from TCM four examinations were analyzed by using factor analysis and entropy-reactor of complex system. Results There were 4 syndrome factors related to disease locations of Hp-positive chronic gastritis, including liver, stomach, spleen and gallbladder (gallbladder being given up after clinical and expert questionnaire), and there were 3 of Hp-negative chronic gastritis, including liver, stomach and spleen. There were 9 syndrome factors related to disease nature of Hp-positive or Hp-negative chronic gastritis, including qi deficiency, yin deficiency, yang deficiency, qi stagnation, phlegm, heat, blood stasis, food accumulation and cold. There were 8 basic syndrome types, including para-syndrome of depression-heat in liver and stomach, para-syndrome of spleen-stomach weakness, para-syndrome of damp-heat accumulation, para-syndrome of food stagnation, para-syndrome of spleen cold and stomach heat, para-syndrome of stomach yin deficiency, para-syndrome of liver qi invading stomach and para-syndrome of stasis in stomach collateral. After Chi-square test, the distribution of the syndrome factors related to disease nature had no difference between Hp-positive chronic gastritis and Hp-negative chronic gastritis, but that of basic syndrome types had difference. The results of pairwise comparison showed that Hp infection was significantly correlated to syndrome distribution (P<0.01), and it was most closely related to para-syndrome of stomach yin deficiency and followed by para-syndrome of spleen-stomach weakness, para-syndrome of damp-heat accumulation and para-syndrome of depression-heat in liver and stomach. Conclusion Hp infection is correlated to dampness and heat, especially to yin deficiency. As a kind of external pathogenic factor, the evil nature of Hp is closely related to heat and dampness and more closely to heat, which is easy to cause impairment of yin.

Key words: chronic gastritis, Helicobacter pylori, syndromes, syndrome factors

CLC Number: 

  • R241