主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJIGN UNIVERSITY OF TRADITIONAL CHINE ›› 2014, Vol. 37 ›› Issue (3): 195-198.doi: 10.3969/j.issn.1006-2157.2014.03.011

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Influence of acupuncture in acupoints of the Pericardium Meridian on functional connectivity of resting-state posterior cingulate cortex in health people

HAN Hong-yan1, ZHANG Chi2, YAN Bin2, TONG Li2, LEI Yu2, ZHOU Hao3, HE Qi1   

  1. 1 School of Acupuncture-Moxibustion and Tuina, Henan University of Traditional Chinese Medicine, Henan 450008;
    2 Chinese PLA Information Engineering University;
    3 School of Information Technology, Henan University of Traditional Chinese Medicine
  • Received:2013-12-16 Online:2014-03-30 Published:2014-03-30

Abstract: Objective To study the central mechanism of acupuncture in the Pericardium Meridian (meridian acupoints) in regulating the network of emotion, memory and cognition by applying resting-state functional magnetic image (fMRI). Methods Healthy participants (n=14) were given fMRI, including the first time resting-state scanning (R1), scanning after acupuncture in all acupoints of the Pericardium Meridian (AP) and the second time resting-state scanning (R2). The posterior cingulate cortex (PCC) was chosen as seed point for studying functional connectivity by using REST software. Results The functional connectivity of PCC was enhanced in bilateral middle temporal gyrus and inferior temporal gyrus, and was significantly weakened in left middle frontal gyrus, left inferior gyrus and right cerebellum posterior lobe only under AP state but not under R1 and R2 states. The functional connectivity of PCC was significantly weakened in right cerebellum posterior lobe, right declive, right uvula and right inferior frontal gyrus only under R2 state but not under R1 and AP states. Conclusion After acupuncture in the acupoints of the Pericardium Meridian, the functional connectivity between PCC and prefrontal cortex and cerebellum was inhibited, and that between PCC and temporal cortex was enhanced synchronously. Through the inter regulation of above-mentioned cerebral zones with higher cognitive function, acupuncture can control memory and emotion, which may be the effective mechanism of acupuncture in the acupoints of the Pericardium Meridian in treating the disorders of memory, emotion and cognition.

Key words: acupuncture, Pericardium Meridian, posterior cingulate cortex, functional connectivity

CLC Number: 

  • R245.9