主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJIGN UNIVERSITY OF TRADITIONAL CHINE ›› 2014, Vol. 37 ›› Issue (3): 209-212.doi: 10.3969/j.issn.1006-2157.2014.03.014

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Curative effect of Zishen Yisui Fang on motor symptoms and non-motor symptoms of Parkinson’s disease

CHEN Lu1, CHEN Zhi-gang1, HOU Yue2   

  1. 1 Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078;
    2 Beijing Children’s Hospital, Capital University of Medical Sciences
  • Received:2013-10-20 Online:2014-03-30 Published:2014-03-30

Abstract: Objective To investigate the curative effect of Zishen Yisui Fang on motor symptoms and non-motor symptoms of Parkinson’s disease (PD). Methods The patients (n=60) were randomly divided into treatment group and control group and treated with anti-PD Western drugs for 3 months, and treatment group was additionally given Zishen Yisui Fang. The administration of Western drugs was recorded for 3 months. The Unified Parkinson’s Disease Rating Scale (UPDRS), Motor Function of Parkinson’s Disease Rating Scale (MDRSPD) and 30-item non-motor symptoms screening questionnaire (NMS 30-item) were reviewed at three time points-before treatment, treatment for 1 month and treatment for 3 months. The curative effect of Zishen Yisui Fang on motor symptoms and non-motor symptoms of PD was studied through comparing score changes of these scales. Results In treatment group, the scores of MDRSPD and NMS 30-item had statistical difference (P<0.05) before and after treatment, and scores of UPDRS and NMS 30-item had statistical difference (P<0.05) in 2 groups after 3 months. The dose changes of anti-PD Western drugs had statistical difference (P<0.05) between two groups during treatment. Conclusion Zishen Yisui Fang can relieve the motor symptoms and non-motor symptoms of PD.

Key words: Parkinson’s disease, Zishen Yisui Fang, observation on curative effect

CLC Number: 

  • R289.56