主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJIGN UNIVERSITY OF TRADITIONAL CHINE ›› 2014, Vol. 37 ›› Issue (4): 269-272.doi: 10.3969/j.issn.1006-2157.2014.04.013

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Smashing extraction of baicalin from Huangqin (Radix Scutellariae)

WANG Yue, DU Shou-ying, WU Qing, RONG Kun, YUAN Hang, LI Ying, LI Hui-yun, LU Xian-jin, WEI Chang-ling   

  1. School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100102
  • Received:2013-09-05 Online:2014-04-30 Published:2014-04-30

Abstract: Objective To study the best technology conditions of smashing extraction method for extracting baicalin from Huangqin (Radix Scutellariae). Methods The influence factors on the smashing extraction method were investigated by using orthogonal design taking the extraction rate of baicalin as an index. The extractive rate, extraction time and electricity consumption were compared with other methods reported in literature. Results The best technique of the smashing extraction method for extracting baicalin from Huangqin was as follows: Huangqin was immersed in boiling water (100℃) for 10 min for killing enzyme and retaining baicalin. After filtration, the soak solution was added 65% ethanol (20 times) and given smashing extraction for 2 min, and then merged with extractive solution. Conclusion The smashing extraction method for extracting baicalin from Huangqin is easy and economic with higher extractive rate compared with decocting method and reflux method, which can be taken as a reference for utilization of Huangqin.

Key words: smashing extraction, Huangqin (Radix Scutellariae), baicalin, orthogonal test

CLC Number: 

  • R284.1