主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJIGN UNIVERSITY OF TRADITIONAL CHINE ›› 2014, Vol. 37 ›› Issue (7): 467-471.doi: 10.3969/j.issn.1006-2157.2014.07.007

Previous Articles     Next Articles

TCM syndromes and syndrome factors of nodular goiter

LV Meng1, DENG Wei-fang2, ZHU He1, XIA Zhong-yuan3   

  1. 1 School of Preclinical Medicine, Beijing University of Chinese Medicine, Beijing 100029;
    2 Department of Chinese Surgery, Shanxi University of Traditional Chinese Medicine;
    3 Department of Chinese Surgery, China-Japan Friendship Hospital
  • Received:2014-03-12 Online:2014-07-30 Published:2014-07-30

Abstract: Objective To study the laws of TCM syndromes of nodular goiter through epidemiological survey. Methods The cross-sectional method of epidemiological survey was applied for analyzing the distribution laws of TCM syndromes and syndrome factors in 236 patients with nodular goiter who were eligible to internalized standard. The correlation between syndrome types and age, course of disease, outcomes of thyroid ultrasound and thyroid function was studied. Results The syndrome of liver depression and qi stagnation had the highest percentage (40.3%) and second ones were syndrome of binding of phlegm and stasis (27.5%) and syndrome of liver depression and spleen deficiency (17.4%). The syndrome factors related to disease locations were mainly liver, spleen and kidney, and those related to pathogenesis were qi stagnation, phlegm coagulation and blood stasis. The difference in the diameter of the largest thyroid nodule had no significance among different groups (P<0.05). The index of thyroid function-TSH level was lower in group of dual deficiency of qi and yin compared with other syndrome types (P<0.05). The difference in age had statistical significance among different groups (P<0.05), and age of liver depression and kidney deficiency group was the eldest and that of liver depression and qi stagnation group was younger. The course of disease was longer in liver depression and kidney deficiency group than that in liver depression and qi stagnation group and binding of phlegm and stasis group (P<0.05). Conclusion The most common syndrome types of nodular goiter are syndromes of liver depression and qi stagnation, binding of phlegm and stasis and liver depression and spleen deficiency, and its important pathogeneses are qi stagnation, phlegm coagulation and blood stasis.

Key words: nodular goiter, TCM syndromes, syndrome factors, clinical epidemiology

CLC Number: 

  • R259.813