主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJIGN UNIVERSITY OF TRADITIONAL CHINE ›› 2014, Vol. 37 ›› Issue (11): 736-739.doi: 10.3969/j.issn.1006-2157.2014.11.004

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Correlation between syndrome differentiation of yin-yang and inflammatory markers in patients with severe sepsis and septic shock

MAI Shu-tao, WENG Yan-na, DU Jiong-dong, LAI Fang, HAN Yun   

  1. Second Clinical Medical College,Guangzhou University of Traditional Chinese Medicine, Guangdong 510120
  • Received:2014-05-21 Online:2014-11-30 Published:2014-11-30

Abstract: Objective To investigate the distribution of syndrome differentiation of yin-yang in severe sepsis and septic shock patients, and to study correlation between yin syndrome or yang syndrome with inflammatory markers. Methods Based on the principles of TCM syndrome differentiation, 98 of 208 patients with severe sepsis and septic shock were diagnosed as yin syndrome, and 110 patients as yang syndrome. Acute physiology and chronic health evaluation Ⅱ(APACHEⅡ) score and systemic inflammatory response syndrome (SIRS) score were recorded, as well as 28 d mortality. Lactic acid(LAC), WBC, percentage of neutrophils (NE%), C-reactive protein (CRP) and procalcitonin (PCT) were determined. Results Yin syndrome patients with mean SIRS score 2.51±0.62 were significantly lower than yang syndrome patients with 3.06±0.80(P<0.05). However, PCT in yin syndrome patients were significantly higher than those in yang syndrome patients(P <0.05). No statistically differences were showed in APACHEⅡ score, WBC, NE% and CRT. In yin syndrome patients, 72 of 98 were survival (survival group)and 26 were dead(death group). APACHEⅡscore and NE% in survival group with yin syndrome were significantly lower than death group(P<0.05). APACHEⅡ score and PCT in survival group (n=81) with yang syndrome were significantly lower than death group (n=29)(P<0.05). Conclusion Syndrome differentiation of yin-yang can be used in predicting the inflammatory state and prognosis in patients with severe sepsis and septic shock.

Key words: severe sepsis, septic shock, syndrome differentiation of yin-yang, inflammatory

CLC Number: 

  • R269.31