主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJIGN UNIVERSITY OF TRADITIONAL CHINE ›› 2014, Vol. 37 ›› Issue (11): 786-788.doi: 10.3969/j.issn.1006-2157.2014.11.015

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Near-infrared spectroscopy for rapid detection of alcohol extract of Jingutongxiao pill

LEI Jing-wei, ZHANG Qiang, BAI Yan, LI Lei, FAN Ming-yue   

  1. Henan University of Traditional Chinese Medicine, Henan 450046
  • Received:2013-12-15 Online:2014-11-30 Published:2014-11-30

Abstract: Objective To determine rapidly the concentration of alcohol extract of Jingutongxiao pill by using near-infrared (NIR) spectroscopy and chemometrics methods. Methods The contents of alcohol extract of 100 batches of Jingutongxiao pill were determined and NIR spectrograms were collected. Partial least squares (PLS) combined with second derivative (SD) was used as spectral processing options. The NIR calibration model of alcohol extracts was established by TQ 8.0 software combined with PLS. Results There were 7 main factors in the quantitative model, whose range was between 8 116.04 and 11 983.82 cm-1. The correlation coefficient of calibration (R2) was 0.99 778, root mean square error of cross validation (RMSEC) was 0.0376, and external prediction deviation(RMSEP)was 0.547. Predicted average relative error was 2.39%. Conclusion The quantitative model established by using near-infrared spectroscopy for determination of alcohol extract of Jingutongxiao pills is rapid, simple and accurate.

Key words: Jingutongxiao pills, alcohol extract, near-infrared spectroscopy, quantitative model

CLC Number: 

  • R284.1