主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJIGN UNIVERSITY OF TRADITIONAL CHINE ›› 2015, Vol. 38 ›› Issue (1): 53-56.doi: 10.3969/j.issn.1006-2157.2015.01.012

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Correlation between serum cell adhesion molecules and TCM syndromes in patients with dyslipidemia

LI Lu,GUO Yang-zhi,YANG Hui-min#,WANG Lin, LI Zhen-yu   

  1. Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700
  • Received:2014-10-20 Online:2015-01-30 Published:2015-01-30

Abstract: Objective To explore the influence of dyslipidemia on serum soluble intercellular adhesion molecule-1(sICAM-1) and soluble vascular cell adhesion molecule-1 (sVCAM-1), and the relationship between TCM syndromes and serum lipemia, cell adhesion molecules. Methods TCM syndromes of 120 patients with dyslipidemia were determined, and whose serum TC,TG, HDL-C, sICAM-1and sVCAM-1 were test, compared with those of 20 healthy persons (normal group). Results The distribution of TCM syndromes of patients was as the following: liver-kidney yin deficiency(n=49), yin deficiency with yang hyperactivity (n=31), phlegm turbidity obstruction(n=25), spleen-kidney yang deficiency (n=10), qi stagnation and blood stasis(n=5). Furthermore, serum cell adhesion molecules in patients was significantly higher than normal group (P<0.05). Compared with liver-kidney yin deficiency group and yin deficiency with yang hyperactivity grouop, TC increased significantly in qi stagnation and blood stasis group; while TG in qi stagnation and blood stasis group increased compared with phlegm turbidity obstruction group (P<0.05). Conclusion The syndrome of liver-kidney yin deficiency, yin deficiency with yang hyperactivity and phlegm turbidity obstruction are main TCM syndromes. TC level can be used to be one of diagnose references in pattern of qi stagnation and blood stasis. And the levels of sICAM-1 and sVCAM-1 increase in patients with dyslipidemia.

Key words: dyslipidemia, serum cell adhesion molecules , TCM syndromes

CLC Number: 

  • R255.7