主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJIGN UNIVERSITY OF TRADITIONAL CHINE ›› 2015, Vol. 38 ›› Issue (3): 206-208.doi: 10.3969/j.issn.1006-2157.2015.03.013

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Effects of Yifei Huoxue granule on quality of life and pulmonary function in patients with stable chronic obstructive pulmonary disease*

OU Min, ZHANG Chao, SONG Xiu-jie, WU Ni   

  1. Cadre Department of Respiratory Disease, Chinese Navy General Hospital, Beijing 100048
  • Received:2014-04-01 Online:2015-03-28 Published:2015-03-28

Abstract: Objective To explore the effect of Yifei Huoxue granule on the pulmonary function and quality of life in patients with chronic obstructive pulmonary disease (COPD) at stable stage. Methods Altogether 128 stable COPD patients were randomly divided into treatment group (n=68) and control group (n=60). The control group undertook conventional western medicine treatment, while the treatment group was treated with the combination of conventional western medicine and orally administration of Yifei Huoxue granule. On the day before treatment and at the end of the twelve-week treatment, pulmonary function was tested, and the general health status were evaluated by using six-minute walk test (6MWT) and St George’s Respiratory Questionnaire (SGRQ). Results After treatment, FEV1, FEV1% and FEV1/FVC% in treatment group were significantly increased (P<0.05) compared with pre-treatment, while there was no statistical difference in control group. Furthermore, FEV1, FEV1% and FEV1/FVC% in treatment group were significantly higher than those in control group (P<0.05) after treatment. Both respiratory symptom score and total score of SGRQ in treatment group were significantly decreased (P<0.01) after treatment, which were significantly lower than those in control group (P<0.05). Activity score in treatment group was significantly decreased (P<0.05).The value of 6MWT was higher after treatment (P<0.05) in treatment group, but there was no significant difference between treatment group and control group. Conclusion Yifei Huoxue granule improved markedly pulmonary function exercise tolerance and quality of life of COPD patients.

Key words: Yifei Huoxue granule, stable chronic obstructive pulmonary disease, pulmonary function, quality of life, exercise tolerance

CLC Number: 

  • R259.63