主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJIGN UNIVERSITY OF TRADITIONAL CHINE ›› 2015, Vol. 38 ›› Issue (8): 566-568.doi: 10.3969/j.issn.1006-2157.2015.08.013

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The effects of external use of Zibai Gel on cervical high-risk human papilloma virus infection: a clinical observation*

XU Kai1, XUE Xiao-ou2#, MA Xiu-li2, QIN Lei2   

  1. 1 Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700;
    2 Zhejiang Provincial Hospital of TCM
  • Received:2014-11-14 Online:2015-08-30 Published:2015-08-30

Abstract: Objective To observe the effects of external use of Zibai gel on cervical high-risk human papilloma virus (HR-HPV) infection. Methods 85 cases with cervical HR-HPV infection were recruited and then divided into two groups quasi-randomly. 57 cases in the treatment group were applied with Zibai gel, while 28 cases in control group did not use any medication. The outcome was measured and observed. Results In the treatment group, the load of HR-HPV was reduced in 56 cases (98.24%) compared with only 9 cases (32.14%) in the control group. There was a significant difference between the two groups (Z=-5.770,P<0.05). In the treatment group, clinical symptoms were relieved in 56 cases (98.24%),compared with only 3 cases(10.71%)in the control group. There was a significant difference between the two groups (Z=-7.485,P<0.05). Cases of 12 patients from the treatment group were followed up after six months, and the load of HR-HPV showed no significant difference compared with those at the time right after the treatment (Z=-0.405,P>0.05). Conclusion The external use of Zibai gel could reduce the load of HR-HPV, and convert some of high-risk HPV infection negative. According to the Results in the six-month follow-up observation, the clinical effect was affirmative.

Key words: external use of Zibai gel, leukorrhagia, high-risk human papilloma Virus, clinical research

CLC Number: 

  • R271.917