主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJIGN UNIVERSITY OF TRADITIONAL CHINE ›› 2015, Vol. 38 ›› Issue (9): 635-640.doi: 10.3969/j.issn.1006-2157.2015.09.012

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Comparison of long-term prognosis of chronic heart failure patients with different TCM syndrome elements in real world*

XU Zheng, ZHANG Bingxuan, SONG Qingqiao#, TIAN Yu, HUANG Wei   

  1. Guang' anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053
  • Received:2015-04-03 Online:2015-09-30 Published:2015-09-30

Abstract: Objective To compare the long-term prognosis of chronic heart failure (CHF) patients with different TCM syndrome elements of phlegm stagnation,qi deficiency, yin deficiency, blood statis and yang deficiency. Methods Subjects were 191 CHF inpatients in Guang’anmen Hospital from January 2006 to August 2011. The clinic information of the patients were collected, including general information, incidence and TCM syndrome elements. After discharging from the hospital, all the patients were visited in outpatient or followed up by telephone for years to get the occurrence and duration of all-cause mortality. Results The long-term prognosis of CHF patients with TCM syndromes ranked from the best to the worst: phlegm stagnation, qi deficiency, yin deficiency, blood stasis and yang deficiency (P<0.01). The prognosis of patients with syndrome of phlegm stagnation was better than those without phlegm stagnation (P=0.017); patients with syndrome of qi deficiency had a better prognosis than those without qi deficiency (P=0.011); there was no significant difference in patients with or without yin deficiency (P=0.633); the overall prognosis of blood stasis patients showed no significant difference with non blood-stasis patients (P=0.182), but went worse from the 500th day; the prognosis of patients with syndrome of yang deficiency was worse than patients without yang deficiency (P=0.002). Conclusion The long-term prognosis of CHF patients is definitely poor. The prognosis of CHF patients with different TCM syndromes showed striking difference. Syndrome of qi deficiency and syndrome of phlegm stagnation would be ordinary in early stage of CHF, and syndrome of yin deficiency played a role through the whole progression of CHF. The effect of syndrome of blood stasis could be associated with CHF disease progression, and the prognosis of patients with blood statis was worse. The syndrome of yang deficiency would be the main syndrome in late stage.

Key words: chronic heart failure, long-term prognosis, TCM syndrome elements

CLC Number: 

  • R256.2