主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJIGN UNIVERSITY OF TRADITIONAL CHINE ›› 2015, Vol. 38 ›› Issue (9): 641-644.doi: 10.3969/j.issn.1006-2157.2015.09.013

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Effect of Yupao decoction on follicle blood flow and pregnancy rate in patients undergoing artificial insemination by husband *

LI Nan1,2 , JIN Zhe 1#, LIU Yanxia1   

  1. 1 Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078; 2 Affiliated Hospital of Shaanxi University of Chinese Medicine
  • Received:2015-03-16 Online:2015-09-30 Published:2015-09-30

Abstract: Objective To explore the effects of Yupao decoction (YPD) , a Chinese herbal compound formulated by the method of reinforcing kidney, on the follicle blood flow and pregnancy rate in patients undergoing artificial insemination by husband (AIH) . Methods Altogether 60 infertile women with small follicular ovulation undergoing AIH were divided into control group(n=34) and YPD group(n=26) according to random number table. Patients in control group were induced ovulation by clomiphene, and those of YPD group were taken ovulation induction with orally administration YPD. The pulsatility index (PI) and resistant index (RI) of follicle blood flow at the day of HCG injection and pregnancy rate (PR) were observed. Results PI , RI , PR were dramatically higher in YPD group than those of control group(P<0.05). In YPD group, the clinical PR was 34.61 % (9/26)and cycle PR was 19.56 %(9/46), by the contrast, the clinical PR was 11.76%(4/34) and the cycle PR 6.06%(4/66)in control group. Conclusion TCM kidney-reinforcing method combined with clomiphene could significantly improve the clinical pregnancy rate of patients undergoing AIH. The potential mechanism of combined therapy would exist in the improve ment the follicle quality by increasing follicle blood flow.

Key words: kidney-reinforcing method, artificial insemination by husband (AIH), follicle blood flow, clinical pregnancy rate

CLC Number: 

  • R271.14