主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJIGN UNIVERSITY OF TRADITIONAL CHINE ›› 2015, Vol. 38 ›› Issue (11): 753-755.doi: 10.3969/j.issn.1006-2157.2015.11.008

• Original Article • Previous Articles     Next Articles

Comparison of day and night nonlinear indexes among syndromes differentiationed by excess and deficiency: a study of 243 patients with coronary heart disease*

YANG Yang1, LI Fangjie2#,LI Xia3,YANG Xinchun4, ZENG Hui2, GUO Xiaoyu2, DAI Yuelong2   

  1. 1 Third Affiliated Hospital, Beijing University of Chinese Medicine, Beijing 100029;
    2 WangJing Hospital, China Academy of Chinese Medical Sciences;
    3 Capital Medical University;4 Chaoyang Hospital, Capital Medical University
  • Received:2015-04-20 Online:2015-11-30 Published:2015-11-30

Abstract: Objective To observe the day and night nonlinear indexes in patients with coronary heart disease(CHD)of excess syndrome, deficiency syndrome and syndrome of intermingled deficiency and excess (mingled syndrome), so as to explore the nonlinear characteristics existed objectively in TCM syndromes. Methods Based on the TCM principles of syndrome differentiation, 243 patients were divided into excess syndrome group(excess group, n=44), mingled syndrome group(mingled group, n=148)and deficiency syndrome group(deficiency group, n=51). Three nonlinear indexes of complexity, mean value of correlation dimension and mean value of approximate entropy were calculated based on the data picked up from 24 h dynamic electrocardiogram(Holter)at the six time intervals: 0∶00 to 1∶00, 4∶00 to 5∶00, 8∶00 to 9∶00, 12∶00 to 13∶00, 16∶00 to 17∶00 and 20∶00 to 21∶00. Results The values of the three nonlinear indexes had a feature in common: the highest in excess group and the lowest in deficiency group. Conclusion The differences of three nonlinear indexes among the syndromes of excess and deficiency presented the differences of the nonlinear characteristics and the functional status of autonomic nerves.

Key words: coronary heart disease, syndrome of excess and deficiency, heart rate variability, nonlinear index, autonomic nerves

CLC Number: 

  • R256.22