主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJIGN UNIVERSITY OF TRADITIONAL CHINE ›› 2016, Vol. 39 ›› Issue (5): 390-394.doi: 10.3969/j.issn.1006-2157.2016.05.008

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Improving the quality standard for Jinlian Qingre Capsule*

DIND Rui1, HE Kai1, ZHANG Haixu2, WANG Qing1   

  1. 1 Ningxia Institute for Drug Control,Ningxia 750001;
    2 Ningxia Autononmous Region Hospital of Traditional Chinese Medicine
  • Received:2015-09-16 Online:2016-05-30 Published:2016-05-30

Abstract: Objective To improve the quality standard of Jinlian Qingre Capsule. Methods Chinese Globeflower Flower(Trollii Chinensis Flos, Jinlianhua),Dyers Woad Leaf(Folium Isatidis, Daqingye),Figwort Root(Srophulariae Radix, Xuanshen)and Bitter Apricot Seed(Semen Armeniacae Amarum, Kuxingren)in Jinlian Qingre Capsule were identified using thin layer chromdograph (TLC). The content of vitexin was detected using HPLC with a Phenomenex Luna C18 (2)100A column(250 mm×4.6 mm,5 μm), a mobile phase of acetonitrile- 0.4% ammonium acetate(15∶85)at the flow rate of 1.0 mL/min, detection wave length at 340 nm and the column temperature at 25 ℃. Results Main spots of Chinese Globeflower Flower,Dyers Woad Leaf,Figwort Root and Bitter Apricot Seed in TLC were clear and separated well. A good linearity was obtained for vitexin in the range of 0.06~0.57 μg(r=0.999 9)with mean sample recovery rate of 99.7% and RSD of 2.1%. Conclusion Method of TLC and HPLC established in this study which appears to be highly specific,accurate and repeatable can be used in the quality control of the Jinlian Qingre Capsule.

Key words: TLC, HPLC, Jinlian Qingre Capsule, vitexin , quality standard

CLC Number: 

  • R284.2