主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJIGN UNIVERSITY OF TRADITIONAL CHINE ›› 2016, Vol. 39 ›› Issue (8): 690-695.doi: 10.3969/j.issn.1006-2157.2016.08.015

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Clinical characteristics and long-term prognosis of type 2 cardiorenal syndrome patients with blood-stasis pattern*

XU Zheng1,YAN Xiaoqian2,SHANG Xiuyang1,DU Bai1,SHI Wei1,SONG Qingqiao3#   

  1. 1 The Second Clinical Medical College of Zhejiang Chinese Medicine University,Zhejiang 310053;
    2 Department of Nephrology, Tongde Hospital of Zhejiang Province;
    3 Cardiovascular Department, Guang’anmen Hospital,China Academy of Chinese Medical Sciences
  • Received:2016-03-15 Online:2016-08-31 Published:2016-08-31

Abstract: Objective To explore the clinical characteristics and the long-term prognosis of type 2 cardiorenal syndrome (CRS) patients with blood-stasis pattern. Methods 390 cases eligible were divided into CRS group and non-CRS group. After comparing TCM pattern elements between the two groups, we collected the related clinical data. Then all patients were followed-up for 1 810 days to get their final events (survive or dead). Using ROC curves plotted based on the relationship between renal function and long-term prognosis, patients were re-assigned into renal function level groups to try to find out the distribution of TCM pattern and the relationship of blood-stasis pattern with renal function or with modern medical indices. Results Blood-stasis pattern was positive correlated with renal function of chronic heart failure (CHF) patients (P=0.027), but was negative correlated with qi deficiency pattern or yang deficiency pattern, maybe due to the progression of CRS. Conclusion The important effect of blood-stasis pattern on the occurrence and development was proved, and the blood-stasis pattern may indicate the deterioration, dysfunction of heart leading to dysfunction of kidney.

Key words: cardiorenal syndrome(CRS), renal function, blood-stasis pattern, prognosis

CLC Number: 

  • R259.41