主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJIGN UNIVERSITY OF TRADITIONAL CHINE ›› 2016, Vol. 39 ›› Issue (11): 949-954.doi: 10.3969/j.issn.1006-2157.2016.11.012

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Influence of Fructus Chebulae water solution on quality of Mongolian medicine Aconiti Kusnezoffii Radix Praeparata

LIU Shuai, LI Weifei, LI Yan, XU Jinkai, LIU Xiaoyan, LI Fei, DU Hong#   

  1. School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102
  • Received:2016-06-06 Online:2016-11-30 Published:2016-11-30

Abstract: Objective To study the influence of different concentration of Fructus Chebulae (Hezi) water solution on the quality of Aconiti Kusnezoffii Radix Praeparata (Zhicaowu), so as to optimize the processing technology and to find out the principle of detoxification of Hezi in processing. Methods Taking Hezi water solution with different concentration as the excipients, pH and content of total tannins were determined. Then content of six alkaloids, indicator of toxic effect, in Zhicaowu were measured by reversed-phase HPLC. Results With the increasing of the concentration of Hezi water solution, the content of total tannins increased, pH decreased at first, then kept stable, and the total six alkaloids increased slowly followed by irregularity. When the content ratio of Caowu to Hezi was 2∶1, consistent with Standard of Inner Mongolia Mongolian Medicines, the total alkaloids content was least. Conclusion Concentration of Hezi water solution and storage time changed the content of alkaloids in Zhicaowu. The content ratio of Hezi to Caowu recorded in Standard of Inner Mongolia Mongolian Medicines (in 1986) was scientific and valid.

Key words: Aconiti Kusnezoffii Radix prepared with Fructus Chebulae, processing, excipients, alkaloids content, pH, tannin

CLC Number: 

  • R283.1