主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJIGN UNIVERSITY OF TRADITIONAL CHINE ›› 2017, Vol. 40 ›› Issue (7): 607-612.doi: 10.3969/j.issn.1006-2157.2017.07.014

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Distribution characteristics of TCM patterns and pattern factors in patients with coronary heart disease-induced chronic heart failure complicated by hypertension*

LUO Liangtao1,2, GUO Shuzhen1, ZHANG Peng1,3, ZHAO Huihui1, WANG Juan1, WANG Wei1#   

  1. 1 School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China;
    2 School of Traditional Chinese Medicine, Capital University of Medical Sciences, Beijing 100069, China;
    3 Department of Cardiology, Chinese Medicine Hospital of Wuhan City, Hubei 430000, China
  • Received:2017-03-15 Online:2017-07-10 Published:2017-07-10
  • Supported by:
    Chinese Administration of Traditional Chinese Medicine (No. 200807007), New Century Talent Support Program of Ministry of Education (No. NCET-13-0692),National Natural Science Foundation of China (No. 81470191, No.81503400)

Abstract: Objective To compare the influences of hypertension on TCM pattern factors and pattern combinations in patients with coronary heart disease-induced chronic heart failure (CHD-CHF), and provide some reference for pattern differentiation and classification of CHD-CHF. Methods The patients with CHD-CHF (n=252) were chosen from 14 cooperation clinical units through multi-center cross-section study, and then all patients were divided, according to whether they are complicated by hypertension or not, into CHD-CHF+hypertension group and CHD-CHF group. The distribution rules of sex, age, types of heart failure, cardiac grades, pattern factors related to disease nature, pattern factors related to disease locations and pattern combinations were compared between 2 groups for conducting statistical analysis and rules investigation. Results The comparisons in sex, age and heart function had no difference between 2 groups. The pattern factors related to disease nature with the highest occurrence frequency were qi deficiency, blood deficiency and yin deficiency in 2 groups, but occurrence frequency of qi deficiency was lower in CHD-CHF+hypertension group than that in CHD-CHF group (P<0.01). The pattern factors related to disease locations were heart and meanwhile involved spleen, lung, kidney and liver, and there was no significant difference between 2 groups (P>0.05). The pattern combinations were almost multi-factor combinations in 2 groups, and 2-factor combination was more in CHD-CHF+hypertension group than that in CHD-CHF group (P<0.05). The most common pattern types were pattern of qi deficiency and blood stasis, and pattern of dual deficiency of qi and yin with blood stasis in CHD-CHF+hypertension group. Conclusion The percentage of qi deficiency reduces in pattern factors related to disease nature, 2-factor combination is more in pattern combinations, and pattern of qi deficiency and blood stasis and pattern of dual deficiency of qi and yin with blood stasis are the most common pattern types in patients with CHD-CHF complicated by hypertension.

Key words: chronic heart failure, coronary heart disease, hypertension, pattern factors, patterns

CLC Number: 

  • R259.44