主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJIGN UNIVERSITY OF TRADITIONAL CHINE ›› 2017, Vol. 40 ›› Issue (8): 693-698.doi: 10.3969/j.issn.1006-2157.2017.08.012

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Correlation between pattern elements of disease nature and common pulse manifestation in 801 patients with viral hepatitis cirrhosis*

ZHAO Lihong1,WANG Tianfang1#,XUE Xiaolin1,WU Xiuyan1,LI Ning1,LI Yonggang2,LI Xin3,CHEN Shengduo4,SUN Fengxia5,LI Xiuhui6,MAO Dewen7,LIU Yanling8,ZHANGChang9,LIU Wen10,ZHANG Qiuyun11   

  1. 1 Beijing University of Chinese Medicine, Beijing 100029, China;
    2 Chinese PLA 302 Hospital, Beijing 100039, China;
    3 Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China;
    4 Chinese Medicine Hospital of Hubei Province, Hubei 430061, China;
    5 Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China;
    6 Beijing You’an Hospital, Capital Medical University, Beijing 100069, China;
    7 First Affiliated Hospital of Guangxi College of Chinese Medicine, Guangxi 530023, China;
    8 Xiyuan Hospital, CACMS, Beijing 100091, China;
    9 Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078,China;
    10 Beijing Hospital of Traditional Chinese Medicine, Beijing 100010, China;
    11 School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, China
  • Received:2017-03-01 Online:2017-08-10 Published:2017-08-10
  • Supported by:
    National Program on Key Basic Research Project (973 Program)(No.2011CB505105), National Natural Science Foundation of China(No. 81473598)

Abstract: Objective To enrich the clinical meanings of common pulse manifestations, and to explore mechanisms of those pulses by analyzing the correlation between pattern elements of disease nature and common pulse manifestations in patients with viral hepatitis or cirrhosis based on the combination of pattern and diseases. Methods A national multicenter cross-sectional epidemiological survey was conducted to collect TCM symptoms, tongue manifestations and pulse conditions(including depth, frequency, width, length, hardness, and frequency of pulse)of patients with viral hepatitis or cirrhosis. The survey questionnaire used the Information Collection form of Vital Hepatitis Cirrhosis drafted by the research group. Standard of Hepatitis Cirrhosis Pattern Elements Differentiation was made to identify patterns and pattern elements.Descriptive statistics such as frequency and rate, Chi-square test,and correlation analysis were used.Results Pulses of 801 patients were collected. Pulses with occurrence rate above 20% was defined as common pulse manifestations, in which wiry pulse accounted for 75.2% (n=602);thready pulse,29.0 % (n=279);deep pulse 29% (n=232); and slippery pulse, 23.1% (n=185). There was positive correlation between wiry pulse and blood stasis and qi stagnation (correlation coefficient was 0.141 and 0.166 respectively,P<0.05).There was positive correlation between slippery pulse and yin deficiency and damp heat (correlation coefficient were 0.093 and 0.131 respectively,P<0.05). There was positive correlation between deep pulse and qi deficiency and yang deficiency(correlation coefficient was 0.099 and 0.111 respectively, P<0.05). There was positive correlation between thready pulse pulse and yin deficiency,qi deficiency, yang deficiency and water retention(correlation coefficient was 0.089,0.109,0.105 and 0.075 respectively, P<0.05). Conclusion There is a certain correlation between pattern elements and common pulse manifestations in viral hepatitis cirrhosis patients.

Key words: viral hepatitis cirrhosis, pulse manifestation, pattern elements of disease nature

CLC Number: 

  • R575.2