主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJIGN UNIVERSITY OF TRADITIONAL CHINE ›› 2018, Vol. 41 ›› Issue (7): 611-616.doi: 10.3969/j.issn.1006-2157.2018.07.014

Previous Articles    

Blood flow changes in sinew bind point in healthy people and focus of bound sinew in patients with knee osteoarthritis observed based on laser speckle imaging*

Zhang Xiaoqing, Dong Baoqiang#, Lin Xingxing, Zhang Zhixing, Mai Ke   

  1. College of Acupuncture and Moxibustion, Liaoning University of Traditional Chinese Medicine, Liaoning 110847, China
  • Received:2018-01-20 Online:2018-07-30 Published:2018-07-30
  • Supported by:
    National Natural Science Foundation of China (81574050), Science and Technology Development Guided by Central Commission from the Ministry of Science and Technology of China (No.2016007025), Innovation Team of Liaoning Province Universities and Colleges (No.LT2015016)

Abstract: Objective To observe the difference in blood flow (BF) between physiologic sinew bind point and pathologic focus of bound sinew by using laser speckle imaging (LSI) in patients with knee osteoarthritis (KOA). Methods The patients with KOA of gallbladder meridian type diagnosed by pattern differentiation of meridian sinew (n=100) were chosen into KOA group, and healthy volunteers (n=100) were chosen into health group. The average BF [10 frames were counted and mean value was calculated (PU)] was observed, recorded and compared after needling distal lingxiaci of the same meridian sinew in 5 sinew bind points (focuses of bound sinew) including linghouci, yanglingci, feiguxiaotou, chengfeijian and chengguci before, during and after needling (5 min, 10 min, 15 min, 20 min) by using moor FLPI-2 system. Results Before needling, BF was higher in linghouci, yanglingci, feiguxiaotou, chengfeijian and chengguci in KOA group than that in health group (P<0.001). During needling, BF was higher in linghouci, yanglingci, feiguxiaotou, chengfeijian and chengguci in KOA group than that in health group (P<0.001). After needling, BF was higher in linghouci, yanglingci, feiguxiaotou, chengfeijian and chengguci in KOA group than that in health group at all time points (P<0.05, P<0.01, P<0.001). Conclusion BF shows a significant ascending feature of LSI in focuses of bound sinew compared with sinew bind points, which may be related to that focuses of bound sinew can reflect disease conditions.

Key words: meridian sinew, focus of bound sinew, sinew bind points, laser speckle imaging, blood flow

CLC Number: 

  • R274.684.3