主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE ›› 2019, Vol. 42 ›› Issue (3): 226-234.doi: 10.3969/j.issn.1006-2157.2019.03.008

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Characteristics of depression pattern based on depression, anxiety and somatoform disorders*

Li Xin1, Wang Liwei2, Li Jingwei3, Ji Xiaodan3, Wang Ying3, Zhao Jingwei3, Yang Jiangwei4, Zhao Wenfang3, Jiang Jian3#   

  1. 1 Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China;
    2 Huashan Hospital, Fudan University, Shanghai 200040, China;
    3 Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200021, China;
    4 Mental Health Center of Zhejiang Province, Zhejiang 310012, China
  • Received:2018-12-26 Online:2019-03-30 Published:2019-04-02
  • Contact: Prof. Jiang Jian, Ph.D., Chief Physician, Doctoral supervisor. Shuguang Hospital, Shanghai University of Traditional Chinese Medicine. E-mail:jiangjiansg@126.com
  • Supported by:
    National Science and Technology Major New Drug Creation Project (No. 2017ZX09304002), Construction Project of Academic Experience Research Laboratory of Famous and Old Physicians of Traditional Chinese Medicine in Shanghai (No. SHGZS-2017024), Key Discipline Projects of Clinical Chinese Pharmacology Shanghai Education Commission (No. J50303), Shanghai Youth Doctors Training Program (No. Shanghai Health Personnel 2012105)

Abstract: Objective To discuss the symptoms, pattern manifestations and disease locations related to zang-fu organs of depression pattern of traditional Chinese medicine (TCM) through the clinical survey on patients with depression, anxiety and somatoform disorders. Methods The patients in accordance with internalized standard were divided into group of major depressive disorder (MDD group), group of anxiety disorder (AD group) and group of somatoform disorders (SFD group). All groups were given scoring by using Self-rating Depression Scale (SDS), Self-rating Anxiety Scale (SAS) and Composite Autonomic Symptom Scale (COMPASS-31). The clinical information was collected from 3 groups for reviewing TCM pattern manifestations and TCM diseases. The TCM characteristics in patients with depression pattern were analyzed by using methods of frequency statistics, chi-square test, Wilcoxon rank sum test and Spearman correlation analysis. Results ①There were totally 291 cases observed, and 124 in MDD group, 92 in AD group and 75 in SFD group. There were more women and mental workers in 3 groups (P>0.05). ②The average numbers of symptoms were (5.98±3.03) in 3 groups, and the more severe the condition, the more the symptoms in MDD group and AD group (P<0.05). ③The scores of COMPASS-31 were positively correlated to symptom numbers in different groups and in combined 3 groups (P<0.05). ④The patients with only psychosomatic symptoms or somatic symptoms accounted for 1.37% and 38.49%, and those with two of them accounted for 60.14%. ⑤The most common clinical manifestations were in spleen-stomach disease system, and secondly in qi-blood-fluid-humor disease system and heart disease system. Compound pattern manifestations were more than simple pattern manifestations. The disease locations related to zang-fu organs were mostly in heart system (44.67%), and secondly in systems of liver, spleen, kidney, stomach, gallbladder and lung. The scores of COMPASS-31 were the highest in kidney disease system. The disease names were the most in heart disease system and secondly in qi-blood-fluid-humor disease system, liver disease system, spleen-stomach disease system and kidney disease system. Conclusion The clinical manifestations of TCM depression pattern appear mostly in the form of somatic symptoms with higher dispersion in pattern properties. The disease locations related to zang-fu organs are mainly heart, liver and spleen involving many disease names.

Key words: depression, anxiety, somatoform disorders, depression pattern, concealed depression pattern

CLC Number: 

  • R277.7