主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE ›› 2019, Vol. 42 ›› Issue (9): 787-792.doi: 10.3969/j.issn.1006-2157.2019.09.014

• Clinical Studies • Previous Articles    

Comparative study on distribution of pattern elements and results of different methods of pattern differentiation in cases of non-small cell lung cancer*

He Zuomei1, Huang Huiyong2, Gao Wenhui3, Xu Yun4, Li Liang3, Shao Feng3,Zeng Puhua1#   

  1. 1 Hunan Academy of Traditional Chinese Medicine Affiliated Hospital, Hunan 410006, China;
    2 Hunan Administration of Traditional Chinese Medicine, Hunan 410008, China;
    3 Hunan University of Chinese Medicine, Hunan 410208, China;
    4 The First People’s Hospital of Xiangtan City, Hunan 411101, China
  • Received:2019-03-24 Online:2019-09-30 Published:2019-09-27
  • Contact: Zeng Puhua, Chief Physician, Ph.D. Hunan Academy of Traditional Chinese Medicine Affiliated Hospital. No. 58 Lushan Road, Yuelu District, Changsha 410006. E-mail: zph120@126.com
  • Supported by:
    Natural Science Foundation of Hunan Province (No.2016JJ4067), Hunan Engineering Research Center Project for Anti-Tumor Chinese Herbal Medicine Innovation Technology (No. High Technology of Development and Reform Commission in Hunan 2015-1085), Science and Technology Project of Hunan Province (No.22016SK2034)

Abstract: Objective To explore case records of non-small-cell lung cancer (NSCLC) through data mining to obtain laws of TCM pattern differentiation of NSCLC, which provide reference for clinical pattern differentiation and treatment of NSCLC. Methods This study excavated information obtained by four diagnostic methods of 7435 non-small cell lung cancer cases, and conducted pattern element differentiation through the “Wenfeng-III Chinese Medicine (Assisted) Diagnosis and Treatment System”. It also analyzed pattern elements from case records by clinicians. The distribution of pattern elements in non-small cell lung cancer was identified, and clinician pattern differentiation and “Wenfeng-III Chinese Medicine (Assisted) Diagnosis and Treatment System” pattern differentiation were compared to analyze the differences. Results An analysis of doctors’ pattern differentiation in case records showed that the elements concerning the location of the disease were mainly spleen (1910 times), and lung (1608). The elements related to the nature of the disease included mainly qi deficiency (6751), blood stasis (6572), fire (heat, toxin) (6331), yin deficiency (5657), and phlegm (1242). An analysis of pattern differentiation results obtained by “Wenfeng-III Chinese Medicine (Assisted) Diagnosis and Treatment System” showed that the elements concerning the location of the disease were mainly lung (7371), chest (1837), kidney (1417), heart (1358), and stomach (1074). The elements related to the nature of the disease included mainly yin deficiency (3507), qi deficiency (3323), phlegm (3204), blood stasis (2542), and fire (heat, toxin) (1622). Conclusion The element concerning the location of the lung cancer was primarily lung and the elements related to the nature of the disease included mainly yin deficiency, qi deficiency, phlegm, blood stasis, and fire (heat, toxin). The pattern differentiation results by “Wenfeng-III Chinese Medicine (Assisted) Diagnosis and Treatment System” are more in line with the distribution of clinical prescriptions.

Key words: non-small cell lung cancer, pattern element, pattern differentiation

CLC Number: 

  • R259.734