主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE ›› 2020, Vol. 43 ›› Issue (3): 248-251.doi: 10.3969/j.issn.1006-2157.2020.03.011

• Clinical Studies • Previous Articles     Next Articles

Prevention and treatment of early interstitial lung disease by dissolving mild blood stasis*

Gong Xuefeng1,2, Cui Hongsheng2#, Ren Peizhong1,2, Chen Qiuyi1,2   

  1. 1 Beijing University of Chinese Medicine, Beijing 100029, China;
    2 Respiratory Department, The Third Affiliated Hospital of Beijing University of Chinese Medicine, Beijing 100029, China
  • Received:2019-03-14 Published:2020-04-13
  • Contact: Prof. Cui Hongsheng, Ph.D., Doctoral Supervisor. The Third Affiliated Hospital of Beijing University of Chinese Medicine. No. 51 Xiaoguan Street, Chaoyang District, Beijing 100029. E-mail: Hshcui@sina.com

Abstract: Static blood is the pathological product and pathogenic factor of blood stagnation in the body according to traditional Chinese medicine. Based on clinical practice, the concept of “mild blood stasis” was proposed to denote the early pathological state during the formation of blood stasis, which exists in the initial stage of many diseases. To be specific, mild blood stasis refers to the pathological state in which blood flow is slightly stagnant or blood stasis occurs only in a few unnoticeable places. It is characterized by blood stasis that is tangible but not easily noticed, blood that is stagnant but not yet causing blockage, diseases that are chronic and complication with other pathogenic factors. At the early stage of interstitial lung disease (ILD), as the condition is mild and manifestations of blood stasis are not prominant, harmonizing collaterals to remove blood stasis can produce a satisfactory effect. Therefore, early ILD is believed to be closely related to “mild blood stasis” in that its core pathogenesis is that disharmony between meridians and collaterals, qi stagnation and phlegm coagulation cause mild blood stasis. Clinically, it is manifested as symptoms like cough, shortness of breath and chest oppression, signs like clubbing of the fingers or toes, crackles on auscultation and other signs and changes in medical imaging results. Based on the understanding of mild blood stasis, this paper explores the prevention and treatment of early-stage ILD by harmonizing collaterals to remove blood stasis. Therapies to boost qi, nourish and invigorate blood, rectify qi and dissolve phlegm can be used to regulate lung collaterals, dispel pathogen and remove turbidity so that onset and progression ILD can be prevented. In other words, mild blood stasis can be dissolved to reverse pulmonary interstitial fibrosis progression.

Key words: mild blood stasis, interstitial lung disease, harmonizing collaterals to dissolve blood stasis, theoretical perspective and methodology

CLC Number: 

  • R256.1