主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE ›› 2020, Vol. 43 ›› Issue (3): 259-264.doi: 10.3969/j.issn.1006-2157.2020.03.013

• Clinical Studies • Previous Articles    

Preliminary study of difference in TCM pattern types between patients with Type I and those with Type II endometrial cancer*

Chen Huifang1, Liu Xiaoli2, Xie Wei2, Liu Jun1, Xue Xiaoou2#   

  1. 1 Beijing University of Chinese Medicine, Beijing 100029, China;
    2 Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China
  • Received:2019-09-24 Published:2020-04-13
  • Contact: Prof. Xue Xiaoou, Ph.D., Chief Physician, Doctoral Supervisor. Dongzhimen Hospital, Beijing University of Chinese Medicine. No.5 Haiyuncang Road, Dongcheng District, Beijing 100700. E-mail: pro_xue@163.com

Abstract: Objective To explore the distribution of TCM patterns in patients with type I endometrial cancer (EC) and those with type II EC and patients’differences in age, endometrial thickness and body mass index (BMI), in order to provide a theoretical basis for the prevention and treatment of endometrial cancer with traditional Chinese medicine. Methods Clinical data of 87 EC patients were retrospectively analyzed, and differences in TCM pattern, age, endometrial thickness and BMI between type I and type II EC patients were identified. Results The 67 patients with type I EC were mainly diagnosed as having the pattern of spleen-kidney yang deficiency, and the 20 patients with type II EC liver-kidney yin deficiency. There was statistically significant difference between the two groups (P<0.05). The average age of type I EC patients who were of or after childbearing age was younger than that of type II EC patients who were all after childbearing age. There was statistically significant difference between the groups (P<0.05). Average preoperative endometrial thickness of patients with type I EC was greater than that of patients with type II EC with statistically significant difference (P<0.05). The percentage of overweight patients with type I EC is higher than that of overweight patients with type II EC and there was statistically significant difference between the two (P<0.05). The percentage of type I EC patients with hypertension, diabetes and dyslipidemia was higher than that of type II EC patients but there was no statistically significant difference between them (P>0.05). Conclusion Type I EC patients mainly suffered from spleen-kidney yang deficiency, while Type II EC patients liver-kidney yin deficiency. There were differences in age, endometrial thickness and BMI between the two groups. Treatment should be tailored to the specific conditions of patients based on pattern differentiation to give full play to the advantages of TCM in the prevention and treatment of EC.

Key words: Type I endometrial carcinoma, Type II endometrial carcinoma, TCM pattern type, endometrial thickness, body mass index

CLC Number: 

  • R273