主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE ›› 2020, Vol. 43 ›› Issue (8): 696-701.doi: 10.3969/j.issn.1006-2157.2020.08.013

• Clinical Studies • Previous Articles     Next Articles

TCM constitution types of gestational diabetes mellitus and their correlation to complications during pregnancy and childbirth*

Wang Jingshang1, Wu Ying2, Liu Xiaowei2, Li Yuan2, Guo Cuimei2, Wu Ying1, Yin Xiaodan1, Li Xianrui1, He Junqin1#   

  1. 1 Department of Traditional Chinese Medicine, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China;
    2 Department of Obstetrics, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China
  • Received:2020-04-14 Online:2020-08-30 Published:2020-08-27
  • Contact: He Junqin, M.A., Chief Physician, Master’s Supervisor. Department of Traditional Chinese Medicine, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, No.251 Yaojiayuan Road, Chaoyang District, Beijing 100026. E-mail: junqinhe@sina.com
  • Supported by:
    Beijing TCM Science & Technology Development Fund (No. JJ2016-22), Beijing Outstanding Talent Cultivation Program (No. 2015000021469G216), Special Funding Support for Clinical Medicine Development, Beijing Municipal Administration of Hospitals (No. ZYLX201510), Top Talent Training Program, Beijing Municipal Administration (DFL20151301)

Abstract: Objective To observe the TCM constitution types of gestational diabetes mellitus (GDM), and their correlation to complications during pregnancy and childbirth. Methods 144 cases who took routine pregnancy check-up in Beijing Obstetrics and Gynecology Hospital, Capital Medical University, were enrolled, including GDM group and control group (no pregnancy complications) (n=72). The levels of fasting blood glucose (FBG), glycosylated hemoglobin (HBA1c) and glycosylated serum protein (GSP) were measured on enrollment. The TCM constitution identification was done on enrollment and before delivery. The occurrence of complications during pregnancy and childbirth were recorded. Results The levels of FBG, HBA1c and GSP in the GDM group were significantly higher than those in the control group (P<0.01). The proportion of biased constitutions in the GDM group was significantly higher than that in the control group (P<0.01). On enrollment, the most common TCM constitution types in the GDM group were Yin Deficiency Constitution and Phlegm-Dampness constitution, accounting for 27.78% and 20.83% respectively. Before delivery, the proportion of Yin Deficiency Constitution and Phlegm-Dampness Constitution in the GDM group were 26.4% and 18.1% respectively. The incidence of complications during pregnancy and delivery in the GDM group was significantly higher than that in control group (P<0.05). Yin Deficiency, Qi Deficiency, Dampness-Heat and Phlegm-Dampness were the four constitution types with the highest incidence of complications during pregnancy and childbirth in the GDM group, which were significantly higher than those in the control group. In the GDM group, the complications rates ofthe Yin Deficiency Constitution were all higher than that of Balanced Constitution(P<0.05). Conclusion Patients with GDM seem to be more likely to have biased constitution types, especially Yin Deficiency and Phlegm-Dampness Constitutions. Meanwhile the incidence of complications during pregnancy and perinatal period in GDM patients with Yin dificiency Constitution seems to be higher than those with a Balanced Constitution. The study provides clinical reference for early prevention and treatment.

Key words: TCM constitution, gestational diabetes mellitus (GDM), complications during pregnancy and childbirth

CLC Number: 

  • R271.9