主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE ›› 2021, Vol. 44 ›› Issue (1): 14-18.doi: 10.3969/j.issn.1006-2157.2021.01.003

• Theoretical Studies • Previous Articles     Next Articles

TCM understanding of acute radiation injury from “spleen losing its duty as the guard”*

Wang Lei, Hu Sumin#   

  1. School of Traditional Chinese Medicine,Beijing University of Chinese Medicine,Beijing 100029,China
  • Received:2020-08-10 Online:2021-01-30 Published:2021-01-18
  • Contact: Prof.Hu Sumin,Beijing University of Chinese Medicine.No.11,Beisanhuan Donglu Road,Beijing 100029.E-mail:husm@bucm.edu.cn.
  • Supported by:
    National Natural Science Foundation of China(No.11475035,11675027);Specially Commissioned Project of National Social Science Foundation(No.14@ZH001).

Abstract: The etiology,pathogenesis,diagnosis and treatment of acute radiation injury (ARI) in traditional Chinese medicine (TCM) are still being explored.The theoretical system has not been established yet,which greatly limits the application and development of TCM in radiation protection.In the previous studies,we analyzed the Chinese medicine etiology of ARI and named it ionization toxin.Based on the pathogenic characteristics of ionizing toxin,and the theoretical connotation of “spleen acting as the guard”,we conclude that the core pathogenesis of ARI is “spleen losing its duty as the guard”.At the early stage of ARI,the pathogenesis is ionization toxin injures the spleen.When it progresses,spleen loses its duty as the guard,thus leading to various diseases.At the later stages the recovering spleen starts to expel the pathological products.Understanding the pathogenesis of acute radiation injury in TCM sets the theoretical stage for prevention and treatment.

Key words: acute radiation injury, pathogenesis of TCM, spleen acting as the guard, spleen losing its duty as the guard

CLC Number: 

  • R228