主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE ›› 2021, Vol. 44 ›› Issue (3): 259-265.doi: 10.3969/j.issn.1006-2157.2021.03.011

• Clinical Studies • Previous Articles     Next Articles

Discussion on the relationship between endometriosis and depression and anxiety*

Zhao Ruihua, Zhang Yongjia   

  1. Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China
  • Received:2020-07-23 Online:2021-03-30 Published:2021-03-30
  • Contact: Prof. Zhao Ruihua, Ph.D., Doctoral Supervisor. Guang'anmen Hospital, China Academy of Chinese Medical Sciences. No. 5 Beixian'ge Street, Xicheng District, Beijing 100053. E-mail: rhzh801@126.com
  • Supported by:
    National Natural Science Foundation of China (No.82074485), Key Scientific Research Project for Public Health Development in Beijing (No. 2018-1-4151)

Abstract: Endometriosis, a chronic, highly recurrent and life-long disease, falls into the category of abdominal mass in traditional Chinese medicine. Blood stasis is the basic pathogenesis of EMs and qi stagnation is a key process in EMs formation. Qi stagnation of women is attributable to qi constraint. EMs brings great physical and mental sufferings to patients because of its long disease course, severe symptoms, easy recurrence and unpredictable curative effects. EMs is often accompanied with depression and anxiety symptoms, which can in turn promote the occurrence and development of EMs by amplifying somatic symptoms, reducing therapeutic effects and activating immunosuppression. This is in line with the traditional Chinese medicine understanding of “depression leads to stasis” and “stasis obstructs qi movement”. Based on this, we argue that there is interaction and mutual causality between EMs and depression and anxiety. That qi constraint leads to blood stasis is the main pathogenesis of EMs. Resolving constraint and invigorating blood is the basic treatment. We explore the relationship between EMs and depression and anxiety to emphasize the important role of depression and anxiety in EMs treatment and prognosis, draw clinicians' and researchers' attention to mental health problems of EMs patients, and provide new ideas for TCM diagnosis and treatment strategies of EMs. In this way, the idea of “shifting the essence and changing qi” can be applied to chronic disease management to form TCM management plans of EMs with biopsychosocial characteristics.

Key words: endometriosis, depression, anxiety, depression leads to stasis, chronic disease management

CLC Number: 

  • R271.1