主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE ›› 2021, Vol. 44 ›› Issue (3): 266-271.doi: 10.3969/j.issn.1006-2157.2021.03.012

• Clinical Studies • Previous Articles     Next Articles

Discussion on the etiology and pathogenesis of psoriasis vulgaris*

Liu Aimin1, Zhang Buxin1, Zhao Wei1, Xu Shengdong2   

  1. 1 Department of Dermatology, Henan Province Hospital of TCM / Institute of Dermatology and Venereology, Henan University of Chinese Medicine, Henan 450002, China;
    2 Department of Dermatology, Jiyuan Maternal and Child Health Care Hospital of Henan Province, Henan 454650, China
  • Received:2020-10-15 Online:2021-03-30 Published:2021-03-30
  • Contact: Prof. Liu Aimin, Ph.D., Doctoral Supervisor. Henan Province Hospital of TCM. No. 6 Dongfeng Road, Jinshui District, Zhengzhou 450002. E-mail:liuaimin273@163.com
  • Supported by:
    National Natural Science Foundation of China (No. 81874471), Special Project of TCM Scientific Research in Henan Province (No.2017ZY2072)

Abstract: Based on a review of the understanding of psoriasis-like diseases such as ganxian (干癣, chronic eczema) and baibi (白疕, psoriasis) by generations of TCM physicians, it is believed that the proposal of the three patterns of “blood heat, blood dryness, and blood stasis” in the classic treatment plan was great inheritance and innovation of pattern differentiation and treatment of psoriasis. However, there were still limitations in ideas of pattern differentiation, which made it difficult to objectively and comprehensively reveal the etiology and pathogenesis of psoriasis. In accordance with the theory of correspondence between human beings and nature in Neijing (Internal Classic), incorporating clinical practice and modern research, and based on the holistic “heaven-earth-man” pattern differentiation and the idea of “seeking the root to treat the disease”, the present research discussed the etiology and pathogenesis of psoriasis in an objective and in-depth manner. It was pointed out that cold was an important factor in the occurrence and development of psoriasis. The reason for and mechanism of the fact that psoriasis is often severe in winter and mild in summer were explained. In addition, both the proposed “new plan” and “classic plan” for pattern differentiation and treatment of psoriasis were discussed thoroughly. It is believed that the new plan enjoys both breadth and depth in its ideas of pattern differentiation, is more objective and practical than the classic plan, and warrants validation and promotion.

Key words: psoriasis vulgaris, etiology and pathogenesis, TCM pattern differentiation

CLC Number: 

  • R275