主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE ›› 2021, Vol. 44 ›› Issue (4): 318-322.doi: 10.3969/j.issn.1006-2157.2021.04.006

• TCM Constitution • Previous Articles     Next Articles

Establishing animal constitution models for research on nine classification of TCM constitution*

Wang Ji1, Zhao Xiaoshan2, Zhou Yumei, Wang Qi1#   

  1. 1 National Institute of TCM Constitution and Preventive Medicine, Beijing University of Chinese Medicine, Beijing 100029, China;
    2 School of Chinese Medicine,Southern Medical University
  • Received:2020-05-24 Published:2021-04-29
  • Contact: Prof.Wang Qi,Doctoral Supervisor, Beijing University of Chinese Medicine, No.11 Beisanhuan Donglu Road, Chaoyang Districy, Beijing 100029. E-mail:doctorwang2009@126.com
  • Supported by:
    Beijing Natural Science Foundation (No.81973715)

Abstract: Constitution (Tizhi) of traditional Chinese medicine (TCM) is a newly emerged subject developed in recent years, but there has been no established approaches to establishing such animal models. Based on the constitution theory and “nine classification of TCM constitution”, this paper puts forward several areas of focus in the construction of constitution animal models: firstly, the constitution theory of traditional Chinese medicine should be aligned; secondly, constitution characteristics of different animals should be taken into consideration; thirdly, the evaluation system of animal model according to the characteristics of different constitutions needs to be established. Taking rodents (rats and mice) as examples, the parameters for evaluating eight kinds of abnormal constitution were recommeded. The establishment of animal model of TCM constitution can be used for the following research: in-depth study of the rationale of TCM constitution and its micro biological characteristics; establishment of two-dimensional or three-dimensional model of constitution, disease and pattern in order to explore the correlation between constitution and disease and pattern; efficacy evaluation of the constitution-adjustment effect and mechanism of action; research on the constitution susceptibility to toxicity.

Key words: nine kinds of constitution classification, constitution, animal model

CLC Number: 

  • R229