主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE ›› 2021, Vol. 44 ›› Issue (6): 544-549.doi: 10.3969/j.issn.1006-2157.2021.06.009

• TCM Constitutions • Previous Articles     Next Articles

Distribution of TCM constitution types of 177 patients with allergic rhinitis and its correlation with anxiety and depression*

Wang Yaqi1, Luo Bin1, Zhao Weibo1, Chen Botian2, Wang Ji1#   

  1. 1 National Institute of Traditional Chinese Medicine Constitution and Preventive Medicine, Beijing University of Chinese Medicine, Beijing 100029, China;
    2 Beijing Chaoyang District Jinzhan Second Community Health Service Centre, Beijing 100018, China
  • Received:2021-01-13 Online:2021-06-30 Published:2021-06-25
  • Contact: Prof. Wang Ji, Doctoral Supervisor. Beijing University of Chinese Medicine. No. 11 Beisanhuan Donglu Road, Chaoyang District, Beijing 100029. E-mail: doctorwang2009@126.com
  • Supported by:
    National Natural Science Foundation of China (No. 81973715), Beijing Natural Science Foundation (No. 7202110), TCM Clinical Peak Discipline Construction Project of Pudong New Area Health Commission (No. PDZY-2018-0603)

Abstract: Objective To explore the distribution of TCM constitution types of patients with allergic rhinitis (AR) and its correlation with anxiety and depression. Methods 243 AR cases who visited Guoyitang Clinic, Beijing University of Chinese Medicine, Beijing Hongyitang TCM Hospital, and the clinic of Shanghai East Hospital, Tongji University in 2020 and 200 common subjects without AR were selected. The TCM constitution types of all the subjects were identified and they were evaluated with Generalized Anxiety Disorder(GAD-7) and Patient Health Queationaire-9(PHQ-9). The distribution of the TCM constitution types of 177 AR patients who completed the valid questionnaire and their evaluation results of anxiety and depression were analyzed with Spearman correlation coefficient, and the anxiety and depression state of 180 common subjects who completed the valid questionnaire were statistically analyzed. Results The most common TCM constitution type of the 177 AR patients was the yang-deficiency constitution (22.0%), followed by special-diathesis constitution (20.3%). The number of cases with composite TCM constitution types in the 177 AR patients was 456, of which special-diathesis constitution was the most common (19.7%), followed by yang-deficiency constitution(18.2%). The most common TCM constitution type of those with anxiety and depression among the 177 AR patients was yang-deficiency constitution. Among the 177 AR cases, those with mild to severe anxiety accounted for 28.2%, those with mild to severe depression accounted for 48.6%, and those with mild to severe anxiety and depression accounted for 24.3%. Among the 180 subjects without AR, 21.1% suffered from mild to severe anxiety, 30.0% mild to severe depression, and 14.4% mild to severe anxiety and depression. All biased TCM constitutions were related positively with anxiety and depression state. The qi-stagnation constitution (r=0.642, P=0.001), phlegm-wetness constitution (r=0.303, P=0.001), and blood-stasis constitution (r=0.281, P=0.001) were positively correlated with anxiety. The qi-stagnation constitution (r=0.588, P=0.001), qi-deficiency constitution (r=0.506, P=0.001), and blood-stasis constitution (r=0.447, P=0.001) were positively correlated with depression. The gentleness constitution was negatively correlated with anxiety (r=-0.448, P=0.001) and depression (r=-0.640, P=0.001). Conclusion The yang-deficiency constition and the special-diathesis constitution are the most common TCM constitution types of AR patients. Patients with allergic rhinitis are more likely to develop anxiety and depression than people without AR. The most common TCM constitution type of AR patients with anxiety and depression is the yang-deficiency type. Qi-stagnation constitution, phlegm-wetness constitution and blood-stasis constitution are more positively related to anxiety, and qi-stagnation constitution, qi-deficiency constitution and blood-stasis constitution are more postitive related to depression. However, gentleness constitution was negatively related to anxiety and depression.

Key words: allergic rhinitis, TCM constitution, special-diathesis constitution, anxiety, depression

CLC Number: 

  • R276.1