主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE ›› 2021, Vol. 44 ›› Issue (3): 238-244.doi: 10.3969/j.issn.1006-2157.2021.03.008

• TCM Constitutions • Previous Articles     Next Articles

Constitution characteristics and Chinese herbal prescription of patients susceptible to new coronavirus pneumonia based on data mining*

Chen Ziqin1, Chen Jia1, Chen Bei1, Zhang Yanlin1, Wang Kunxiu1, Luo Zhihui1, Gu Xiaolei1, Yan Peng2, Chen Song1#   

  1. 1 School of Acupuncture, Moxibustion, Orthopaedics and Traumatology, Hubei University of Chinese Medicine / Hubei Provincial Collaborative Innovation Center of Preventive Treatment by Acupuncture and Moxibustion, Hubei 430061, China;
    2 The Second Hospital of Jingzhou, Hubei 430000, China
  • Received:2020-07-23 Online:2021-03-30 Published:2021-03-30
  • Contact: Associate Prof. Chen Song, Ph.D, Master's Supervisor. Hubei University of Chinese Medicine. No.188 Liangdao Street, Wuchang District, Wuhan 430061. E-mail:362573836@qq.com
  • Supported by:
    The Sixth Batch of National Senior TCM Experts' Academic Experience Inheritance Project (No. 2017- 29), National Administration of Traditional Chinese Medicine Qihuang Project (No. 2018-284), Hubei Provincial Young Talent Cultivation Plan (No. 2020-1), Hubei Prestigious TCM Teachers' Workshop Project (No.2018-15), Jingzhou Municipal Science and Technology Innovation Think Tank Research Project (No. JZCXZK202002)

Abstract: Objective To explore the predominant constitution of patients with novel coronavirus pneumonia (COVID-19) and the optimal Chinese medicine diagnosis and treatment plan. Methods Patients diagnosed with COVID-19 and treated in the Second Hospital of Jingzhou were included in the study. Descriptive analysis was made of the constitution survey of hospitalized patients with COVID-19, and statistical analysis was made of effective Chinese medicine prescriptions to mine their core herbs. Results The analysis of the constitutional characteristics of patients susceptible to COVID-19 showed that the proportion of those with wetness-heat constitution was the highest. The statistical analysis of effective prescriptions used during the treatment period of COVID-19 showed that all the effective prescriptions involved a total of 152 herbs, among which the most frequently used was Houpo (Magnolia Bark, Cortex Magnoliae Officinalis). It appeared in 51 prescriptions and the most frequently prescribed dose was 15 grams. In terms of the four properties and five flavors of the herbs, the most commonly used are herbs cold in nature (45.55%) and bitter in flavor (41.55%). In terms of meridian tropism, the most frequently entered meridian was the lung meridian (26.28%). In terms of indications, the herbs most commonly used were those to dissolve phlegm and relieve cough and panting (19.39%). Association rules analysis uncovered 5 core herbs and cluster analysis 3 herb combinations. Conclusion The constitution susceptible to the novel coronary pneumonia was the wetness-heat constitution. During the treatment period, both herbs cold and those warm in property were used to regulate both the lung and the spleen. The treatment principles included mainly these to dispel dampness and remove turbidity, and to free and regulate qi movement. The core herbs were derived from the classic formula Dayuan Yin (Membrane-source Decoction) modified to eliminatie internal disease causes, external causes and causes that are neither internal nor external.

Key words: COVID-19, body constitution, diagnosis and treatment plan, rules of prescribed herbs

CLC Number: 

  • R259