主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJIGN UNIVERSITY OF TRADITIONAL CHINE ›› 2018, Vol. 41 ›› Issue (5): 395-399.doi: 10.3969/j.issn.1006-2157.2018.05.007

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Content and influencing factors of tobeimoside I in Tubeimu from different producing areas analyzed by using group-average clustering method*

Tan Ning, Lu Yang, Xue Yutao, Li Yanping, Zeng Yanling, Du Shouying#
  

  1. School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China;
  • Received:2017-10-25 Online:2018-05-30 Published:2018-05-30
  • Supported by:
    National Major Scientific and Technological Special Project for “Significant New Drugs Development” of China (No. 2014ZX09301306-008), Beijing New-star Plan of Science and Technology (No.XX2015A048)

Abstract: Objective To identify the content of tubeimoside I in Paniculate Bolbostemma from 16 different locations and determine the high-containing locations and influencing factors. Methods The quantitative determination method of tobeimoside I in Tubeimu (Paniculate Bolbostemma, Rhizoma Bolbostematis) in Chinese Pharmacopoeia (2015 Edition) was used to determine the content of tobeimoside I in 16 batches of Tubeimu for deciding producing areas with higher content of Tubeimu and analyzing the influencing factors. The origin producing areas was classified by using group-average clustering analysis method taken content of tobeimoside I as the index. Results The results showed that the content of tobeimoside I was in a range from 1.234% to 3.174% in different producing areas, which was accorded with the requirement of Chinese Pharmacopoeia. The clustering analysis classified 16 producing areas into 4 groups, and content of tobeimoside I was the highest in Tubeimu material produced from Shangluo and Hanzhong. Conclusion The temperature and humidity had influence on Tubeimu material, and content of tobeimoside I was higher in the producing areas with higher temperature and humidity.

Key words: Tubeimu (Paniculate Bolbostemma, Rhizoma Bolbostematis), tobeimoside I in Tubeimu, group-average method, clustering analysis

CLC Number: 

  • R284.1