主 办:北 京 中 医 药 大 学
ISSN 1006-2157 CN 11-3574/R

JOURNAL OF BEIJIGN UNIVERSITY OF TRADITIONAL CHINE ›› 2018, Vol. 41 ›› Issue (11): 885-889.doi: 10.3969/j.issn.1006-2157.2018.11.001

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On inflammation-cancer transformation of chronic gastritis from view of traditional Chinese medicine*

Ding Xia1, Wei Wei2, Shen Hong3, Sun Zeqi1   

  1. 1 Beijing University of Chinese Medicine, Beijing 100029, China;
    2 Wangjing Hospital, China Academy of Chinese Medicine Sciences, Beijing 100102, China;
    3 Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu 210029, China
  • Received:2018-07-15 Online:2018-11-30 Published:2018-11-30
  • Supported by:
    National Natural Science Foundation of China (No. 81630080), National Natural Science Foundation for Youths (No. 81703931); Fundamental Research Funds for the Central Universities in Beijing (No. 2017-JYB-JS-023), Major Research plan of the National Natural Science Foundation of China (No. 91129714), China Postdoctoral Science Foundation (No.150905)

Abstract: The inflammation-cancer transformation of chronic gastritis is a classical model of malignant transformation from chronic uncontrollable inflammation cancer, and traditional Chinese medicine (TCM) plays an important role in delaying, blocking and reversing the progress of this disease. From the perspective of TCM, TCM cognition on inflammation-cancer transformation of chronic gastritis, and the function, value, bottleneck problem and countermeasure of TCM in controlling thus progress are expounded. At present stage, there are relatively few TCM literatures on discussion of inflammation-cancer transformation of chronic gastritis, and no systematic research Results achieved. The TCM theory of “dynamic thinking” and “preventive treatment of disease” plays an important role in the prevention and treatment of inflammation-cancer transformation of chronic gastritis. TCM has advantages in removing causes of disease, alleviating patients’ clinical symptoms and improving the pathological morphology of gastric mucosa. In the process of controlling inflammation-cancer transformation of chronic gastritis, TCM has the characteristics of higher safety, lower drug dependence and good compliance. It is of great significance and value to control the progress of the disease and reduce the incidence of gastric cancer. However, there are still some problems including a lack of systematic ideas of differentiation and treatment in clinical practice, unclear time for intervention of inflammation-cancer transformation of chronic gastritis, and indistinct combined effects with Western medicine at the present stage. The bottleneck problems are manifested as program in scientific research cannot reflect TCM characteristics, systematic mechanism exploration is in shortage, and research Results are difficult to be applied in clinical practice. Therefore, further consideration and measures are needed in controlling inflammation-cancer transformation of chronic gastritis by TCM

Key words: chronic gastritis, gastric cancer, inflammation-cancer transformation, Chinese medicine, review

CLC Number: 

  • R259.733