Application rules of Xiaoqinglong Decoction based on the modern medical records*
2017, 40 (1):
Objective To explore the application rules of Xiaoqinglong Decoction in modern clinical practice, in order to provide a new idea and method for ancient Chinese herbal medicine compound to serve the present days. Methods Retrieving CNKI database, eligible 599 articles were selected through the keyword of “小青龙汤”, with remarkable effect and complete clinical information. Altogether 786 cases from the articles were input Excel table. The disease names, symptoms and the herbal medicineswere standardized, and their frequency were analyzed. Then the primary symptoms of Xiaoqinglong Decoction Syndrome were screened by using Golden Section Method, and the symptoms with frequency of 20 or above were performed cluster analysis including hierarchical clustering, Ward method and Pearson dependency. Results There are 68 western disease names and 45 TCM disease names, and 48 symptoms, 46 herbal medicines, 8 tongue texture, 7 tongue coating and 10 pulse manifestion with frequency of 20 or above. As the consequence, six primary symptoms and 17 significant cluster sets were screened. Conclusion Xiaoqinglong Decoction was undoubtedly used for pulmonary diseases including bronchitis, bronchial asthma, as well as cardiac diseases including cor pulmonale, heart failure arisen from pulmonary diseases, and other diseases due to phlegm and fluid retention. The indications of Xiaoqinglong Decoction were listed as cough, asthma, expectoration, white sputum, pale tongue and white tongue coating, with the accompanied symptoms of yang-deficiency syndrome, blood stasis syndrome, exogenous cold syndrome and interior heat syndrome. The basic pathogenesis of Xiaoqinglong Decoction Syndrome was referred as phlegm and fluid retention accumulated in the lung with the disease location of lung, which could aggravate to yang-deficiency in spleen and kidney, blood stasis in heart vessels or interior heat consuming yin.
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