A comparative study on tongue diagnostic parameters between phlegm-stasis binding pattern and non-phlegm-stasis binding pattern of coronary heart disease at different time points*
2019, 42 (11):
Objective To measure repeatedly the tongue manifestations at different time points in patients with coronary heart disease (CHD)-phlegm-stasis binding pattern (CHD-PSB pattern), and provide Objective evidence for differentiating and diagnosing CHD-PSB pattern based on traditional Chinese medicine (TCM).Methods The eligible subjects were chosen, and the information of 10 indexes, including tongue fur color, tongue fur area, teeth marks, ecchymosis, fissures and thorn-like protrusions, were collected and analyzed by using tongue diagnostic instrument. Firstly, the indexes of tongue manifestations were compared among CHD-PSB patients, non-CHD-PSB patients and healthy persons in the day of hospital admission (the 0th d), and then those indexes were compared between CHD-PSB patients and non-CHD-PSB patients on the 0th d, 5th d and 10th d after they were hospitalized and received treatment.Results There were totally 149 cases been chosen, among them 8 was not accordant with inclusion criteria and 141 were final eligible cases, who were divided into CHD-PSB pattern group (n=83), non-CHD-PSB pattern group (n=58), and health group (n=22) was established in addition. There were 39 cases (24 in CHD-PSB pattern group and 15 in non-CHD-PSB pattern group) received repeated measures at 3 time points. The differences in the area of tongue fur, G value of tongue fur, amount and area of teeth marks, amount and length of fissures, amount and area of ecchymosis, and amount and area of thorn-like protrusions had statistical significance between CHD-PSB pattern group and health group. The differences in amount and area of teeth marks, amount and area of ecchymosis and amount and area of thorn-like protrusions had statistical significance between CHD-PSB pattern group and non-CHD-PSB pattern group. The comparison in the measurement indexes of tongue manifestations of the same pattern types at 3 time points showed that, except of amount and area of thorn-like protrusions in CHD-PSB pattern group, the difference in other indexes had no statistical significance.Conclusion Tongue diagnostic instrument can realize the possibility of objectification and quantification of TCM diagnosis, and the measurement Results can be used as a reference for diagnosis.
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