Objective To establish a method of quantitative determination of patchouli alcohol in Huoxiangzhengqi Soft-Capsules by capillary gas chromatography.Methods The samples of patchouli alcohol were determined by capillary gas chromatography after ultrasound treatment and centrifugation.The chromatographic procedure was performed on the column of HP-5（30 m×0.32 mm×0.25 μm）.The initial temperature was maintained at 170 ℃ for 3 minutes

and then the temperature was raised to 182 ℃ at the speed of 1 ℃/min and maintained for 1 minute.The inlet temperature of samples was at 280 ℃

the detector temperature was at 280 ℃

the flow rate of Nitrogen was 0.6 mL/min

n-octadecane was taken as the internal standard

and FID was used for detection.Results Patchouli alcohol showed a good linear relationship at the range from 0.041 1 mg/mL to 0.411 2 mg/mL in the ratio between peak area and internal standard peak area or concentration（Y=2.94X+0.0128

r=0.999 2）.The average recovery was 98.96%（RSD=1.88%

n=6）.Conclusion The method is accurate

easy and sensitive

which can be used for the quantitative determination of patchouli alcohol in Huoxiangzhengqi Soft-Capsules.