GENG Dong, GUO Rong-juan#. Clinical investigation on TCM symptoms and syndrome factors of generalized anxiety disorder[J]. Journal of Beijing University of traditional Chinese Medicine, 2013, 36(6): 421-425.
GENG Dong, GUO Rong-juan#. Clinical investigation on TCM symptoms and syndrome factors of generalized anxiety disorder[J]. Journal of Beijing University of traditional Chinese Medicine, 2013, 36(6): 421-425.DOI:
Clinical investigation on TCM symptoms and syndrome factors of generalized anxiety disorder
Objective To explore the distribution characteristics of TCM symptoms and syndrome factors of generalized anxiety disorder.Methods The patients with diagnosed generalized anxiety disorder(n=200) were asked to fill in the questionnaire for collecting four examination information.The distribution characteristics of TCM symptoms and syndrome factors were analyzed by applying Hamilton Anxiety Scale(HAMA)、Hamilton Depression Scale(HAMD)
dexcriptive analysis and cluster analysis.The syndrome factors and HAMA scores were given Spearman correlation analysis.Results The first ten symptoms were impatient
irritability
depressed mood
oppression in the chest
sighing
fatigue
palpitation
dreaminess
short breath
heaviness of head and body
lassitude of spirit
laziness to speak
dry mouth and throat and bitter taste in mouth.The syndrome factors included qi stagnation
qi deficiency
fire-heat
blood deficiency
yin deficiency
phlegm syndrome and blood stasis.According to the clustering results
blood deficiency
fire-heat
phlegm syndrome
qi deficiency
qi stagnation and yin deficiency were clustered into one class
and blood stasis was clustered into another class.Qi deficiency and qi stagnation were positively correlated to HAMA scores(P<0.05).Conclusion TCM syndrome factors are mainly qi deficiency and qi stagnation in the patients with generalized anxiety disorder
and the more serious the anxiety is
the higher the scores of these syndrome factors are.