Objective To study the influence of ground cherry’s extraction on antioxidant ability in aging rats induced by D-galactose.Methods All 75 Wister male rats（6 weeks old） were randomly divided into five groups

including the young control group（group 1）

model group（group 2）

low-dose extraction group（10 mg/kg

group 3）

middle-dose extraction group（15 mg/kg

group 4） and high-dose extraction group（20 mg/kg

group 5）

besides other 15 Wister male rats（16 months old） were included in the old control group（group 6）.The rats in group 2

3

4 and 5 were given injection of D-galactose for 5 months.After 5 months the contents of serum malonaldhydic acid（MDA） and liver MDA

activities of superoxide dismutase（SOD） and glutathion peroxidase（GSH-Px） in all groups were detected and compared.Results Compared with the young control group

the content of serum MDA

liver MDA were significantly increased（P<0.01） and the activities of SOD and GSH-Px were significantly decreased（P<0.01） in group 2

but those changes were as the same as those of group 6.The contents of serum MDA and liver MDA in group 3

4 and 5 were significantly decreased compared with those in group 2（P<0.01）

while the activities of SOD and GSH-Px were significantly increased（P<0.01）.Conclusion The extraction of ground cherry can increase the antioxidantive ability of rats in order to delay the consenescence induced by D-galactose.