To study the influence of TCM clinical practice on the development of TCM theories by the way of studying "Life Gate（ mingmen） Doctrine"

including its history

its theoretical framework and the reason for its vicissitude. The rise was in Ming Dynasty and fall was in Qing Dynasty

and decentralization in Foundamental Theory of Traditional Chinese Medicine

a unified compiled teaching book. In Ming Dynasty

Life Gate Doctrine originated from the requirement of interpreting the life-propelling force and the force mechanism

and was established with Neo-Confucianism as its central foundation. But for the reason of lacking practical ground

the doctrine declined in Qing Dynasty. In Foundamental Theory of Traditional Chinese Medicine

the theoretical framework of Life Gate Doctrine was not original

but a new one based on parts of the original framework of "life-propelling force-liver

heart

spleen

lung

kidney viscera-organ". The changes reflected the theoretical construction of "liver controlling dipersion"due to two causes: the changes of mainstream thoughts induced the difference of central structure and central theories

which were mutually exclusive in Life Gate Doctrine whose inherent problems were magnified;throughout

the interpretation of "life-propelling force"was indispensable for TCM theory. In a word

it is undoubtedly significant to study TCM Viscera-Organ Theory and improve clinical practice based on understanding the changes of Life Gate Doctrine.